Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 13/20 | 0.40 |
| ▸ | EDNRB | P24530 | 1/20 | 0.39 |
| ▸ | EDNRA | P25101 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5159629 | 0.93 | PTGDR2 (0.41) | HTR1APTGDR2 | |
| SCHEMBL1845395 | 0.81 | PTGDR2 (0.49) | HTR1APTGDR2 | |
| SCHEMBL5159385 | 0.72 | MAPT (0.39) | — | |
| SCHEMBL1570633 | 0.71 | PTGDR2 (0.50) | HTR1APTGDR2 | |
| SCHEMBL5162020 | 0.71 | MAPT (0.36) | PTGDR2 | |
| SCHEMBL5156725 | 0.71 | MAPT (0.41) | — | |
| SCHEMBL5160136 | 0.69 | SLC18A3 (0.53) | HTR1A | |
| SCHEMBL15016437 | 0.69 | CYP19A1 (0.53) | HTR1A | |
| SCHEMBL5160457 | 0.69 | MAPT (0.38) | — | |
| SCHEMBL5159504 | 0.69 | MAPT (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1748984-A1 | PIPERIDINE DERIVATIVES AS NK1 AND NK3 ANTAGONISTS | Pfizer Products Inc. (US) | 2007-02-07 | — | — | EP | claimed |
| WO-2005110987-A1 | PIPERIDINE DERIVATIVES AS NK1 AND NK3 ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2005-11-24 | — | — | WO | claimed |
| EP-1748984-A1 | PIPERIDINE DERIVATIVES AS NK1 AND NK3 ANTAGONISTS | Pfizer Products Inc. (US) | 2007-02-07 | — | — | EP | disclosed |
| WO-2005110987-A1 | PIPERIDINE DERIVATIVES AS NK1 AND NK3 ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2005-11-24 | — | — | WO | disclosed |