Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CETP | P11597 | 3/20 | 0.42 |
| ▸ | TLR2 | O60603 | 2/20 | 0.41 |
| ▸ | MMP3 | P08254 | 2/20 | 0.40 |
| ▸ | MMP8 | P22894 | 2/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 2/20 | 0.39 |
| ▸ | UGCG | Q16739 | 2/20 | 0.39 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31362254 | 0.86 | CSNK1E (0.49) | CSNK1EL3MBTL1TDP1CETPTLR2 | |
| SCHEMBL31362240 | 0.86 | CSNK1E (0.49) | CSNK1EL3MBTL1TDP1CETPTLR2 | |
| SCHEMBL3429104 | 0.86 | CSNK1E (0.49) | CSNK1EL3MBTL1TDP1CETPTLR2 | |
| SCHEMBL15153556 | 0.86 | CSNK1E (0.49) | CSNK1EL3MBTL1TDP1CETPTLR2 | |
| SCHEMBL29242924 | 0.86 | CSNK1E (0.49) | CSNK1EL3MBTL1TDP1CETPTLR2 | |
| SCHEMBL31399466 | 0.86 | CSNK1E (0.49) | CSNK1EL3MBTL1TDP1CETPTLR2 | |
| SCHEMBL31362251 | 0.86 | CSNK1E (0.49) | CSNK1EL3MBTL1TDP1CETPTLR2 | |
| SCHEMBL6026038 | 0.86 | CSNK1E (0.49) | CSNK1EL3MBTL1TDP1CETPTLR2 | |
| SCHEMBL22749478 | 0.86 | CSNK1E (0.49) | CSNK1EL3MBTL1TDP1CETPTLR2 | |
| SCHEMBL29113328 | 0.86 | CSNK1E (0.49) | CSNK1EL3MBTL1TDP1CETPTLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1751126-A1 | ALKYL CARBAMATE-SUBSTITUTED BUTYROLACTONES SERVING AS LIPASE INHIBITORS | Solvay Pharmaceuticals GmbH (DE) | 2007-02-14 | — | — | EP | disclosed |
| WO-2005080366-A1 | ALKYL CARBAMATE-SUBSTITUTED BUTYROLACTONES SERVING AS LIPASE INHIBITORS | SOLVAY PHARMACEUTICALS GMBH (DE) | 2005-09-01 | — | — | WO | disclosed |