Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 9/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.40 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.40 |
| ▸ | ADAM17 | P78536 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1141430 | 0.95 | TLR7 (0.41) | TLR7TLR8NUDT1ADAM17ALDH1A1 | |
| SCHEMBL1141319 | 0.93 | TLR7 (0.37) | TLR7TLR8NUDT1ADAM17ALDH1A1 | |
| SCHEMBL1141092 | 0.93 | TLR7 (0.40) | TLR7TLR8NUDT1ADAM17ALDH1A1 | |
| SCHEMBL1140954 | 0.91 | TLR7 (0.42) | TLR7TLR8NUDT1ADAM17ALDH1A1 | |
| SCHEMBL1140848 | 0.90 | TLR7 (0.36) | TLR7TLR8NUDT1ADAM17ALDH1A1 | |
| SCHEMBL1140917 | 0.89 | TLR7 (0.40) | TLR7TLR8NUDT1ADAM17MEN1 | |
| SCHEMBL5617020 | 0.86 | TLR7 (0.41) | TLR7TLR8NUDT1MEN1TSHR | |
| SCHEMBL1141106 | 0.86 | TLR7 (0.37) | TLR7TLR8NUDT1ADAM17MEN1 | |
| SCHEMBL5163539 | 0.85 | RXFP1 (0.38) | TLR7TLR8MEN1KMT2A | |
| SCHEMBL1141121 | 0.84 | TLR7 (0.42) | TLR7TLR8NUDT1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765348-A2 | SUBSTITUTED IMIDAZOQUINOLINES, IMIDAZOPYRIDINES, AND IMIDAZONAPHTHYRIDINES | 3M Innovative Properties Company (US) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006028545-A2 | SUBSTITUTED IMIDAZOQUINOLINES, IMIDAZOPYRIDINES, AND IMIDAZONAPHTHYRIDINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2006-03-16 | — | — | WO | disclosed |