Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL5160255

N.N.NC(=O)OP(=O)(O)OC(N)=O

nearest known ligand 0.63

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Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA4 P22748 3/20 0.63
CA1 P00915 2/20 0.52
CA5A P35218 2/20 0.52
CA5B Q9Y2D0 2/20 0.52
PEPD P12955 1/20 0.31
FDPS P14324 1/20 0.30
BLM P54132 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6242978 0.97 CA4 (0.67) CA4CA1CA5ACA5BPEPD
SCHEMBL8438459 0.84 CA4 (0.52) CA4CA1CA5ACA5B
SCHEMBL5154216 0.82
Aminocarbonyl Dihydrogen Phosphate SCHEMBL5160243 0.81 CA4 (0.94) CA4CA1CA5ACA5BPEPD
Aminocarbonyl Dihydrogen Phosphate SCHEMBL2951922 0.81
SCHEMBL27837210 0.80 CA4 (0.62) CA4CA1CA5ACA5BPEPD
SCHEMBL6575772 0.80
Ammonia Solution, Strong SCHEMBL11867425 0.78 CA4 (0.46) CA4CA1CA5ACA5BTDP1
Aminocarbonyl Dihydrogen Phosphate SCHEMBL50374 0.78
Aminocarbonyl Dihydrogen Phosphate SCHEMBL20798017 0.78 CA4 (1.00) CA4CA1CA5ACA5BPEPD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0832970-B1 PROCESS FOR PRODUCING NUCLEOSIDE-5'-PHOSPHATE ESTER AJINOMOTO KK (JP) 2007-01-17 EP disclosed
EP-0857788-B1 Method for producing nucleoside-5'-phosphate ester AJINOMOTO KK (JP) 2003-04-23 EP disclosed
US-6355472-B2 ACID PHOSPHATASE AJINOMOTO CO., INC. (JP) 2002-03-12 US disclosed
US-20020004590-A1 Method for producing nucleoside-5'-phosphate ester MIHARA YASUHIRO (JP) 2002-01-10 US disclosed
US-6207435-B1 MUTANT ACID PHOSPHATASE HAVING DECREASED MICHAELIS CONSTANT FOR A NUCLEOSIDE AND/OR INCREASED TEMPERATURE STABILITY; FOR EFFICIENT PHOSPHORYLATION OF NUCLEOSIDES TO PRODUCE NUCLEOTIDES AJINOMOTO CO., INC. (JP) 2001-03-27 US disclosed
US-6015697-A ECONOMICAL AND EFFICIENT PROCESS BY REACTING A NUCLEOSIDE WITH A PHOSPHATE DONOR GROUP IN PRESENCE OF MUTANT ACID PHOSPHATASE WITH DECREASED MICHAELIS CONSTANT FOR NUCLEOSIDE OR INCREASED TEMPERATURE STABILITY AJINOMOTO CO., INC. (JP) 2000-01-18 US disclosed
US-6010851-A ALLOWING AN ACID PHOSPHATASE HAVING A LOWERED PHOSPHOMONOESTERASE ACTIVITY TO ACT UNDER A CONDITION OF PH 3.0 TO 5.5 ON A NUCLEOSIDE AND A PHOSPHATE GROUP DONOR AJINOMOTO CO., INC. (JP) 2000-01-04 US disclosed
EP-0857788-A2 Method for producing nucleoside-5'-phosphate ester Ajinomoto Co., Inc. (JP) 1998-08-12 EP disclosed
EP-0832970-A1 PROCESS FOR PRODUCING NUCLEOSIDE-5'-PHOSPHATE Ajinomoto Co., Inc. (JP) 1998-04-01 EP disclosed