SCHEMBL5160294

SCHEMBL5160294

C=CC(=O)OCCC[Si](CCCOC(=O)C=C)(CCCOC(=O)C=C)OC

nearest known ligand 0.59

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.59
ALDH1A1 P00352 4/20 0.59
CYP3A4 P08684 2/20 0.59
HPGD P15428 1/20 0.58
TP53 P04637 3/20 0.48
HIF1A Q16665 3/20 0.48
HSD17B10 Q99714 1/20 0.48
THRB P10828 2/20 0.41
ATM Q13315 1/20 0.38
MAPK1 P28482 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HCAR2 Q8TDS4 3/20 0.34
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16537130 0.93 TSHR (0.61) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL534868 0.91 TSHR (0.58) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL16537468 0.89 TSHR (0.59) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL16537540 0.87 TSHR (0.58) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL16536696 0.87 TSHR (0.57) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL16537166 0.86 TSHR (0.56) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL71730 0.85 TSHR (0.59) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL5165890 0.85 TSHR (0.59) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL16286528 0.85 TSHR (0.59) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL16537850 0.85 TSHR (0.59) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220171305-A1 EXTERNAL ADDITIVE PARTICLES, TONER, AND METHOD FOR PRODUCING EXTERNAL ADDITIVE PARTICLES CANON KABUSHIKI KAISHA (JP) 2022-06-02 US disclosed
US-20220128920-A1 EXTERNAL ADDITIVE PARTICLE AND TONER CANON KABUSHIKI KAISHA (JP) 2022-04-28 US disclosed
EP-1211278-B1 Organic - inorganic composite particles and production process thereof NIPPON CATALYTIC CHEM IND (JP) 2007-03-21 EP disclosed
EP-0653663-B1 Organic-inorganic composite particles and production process therefor NIPPON CATALYTIC CHEM IND (JP) 2002-09-18 EP disclosed
EP-1211278-A2 Organic - inorganic composite particles and production process thereof NIPPON SHOKUBAI CO., LTD. (JP) 2002-06-05 EP disclosed
US-6331373-B1 CHARGE STABILITY AND FLUIDITY NIPPON SHOKUBAI CO., LTD. (JP) 2001-12-18 US disclosed
US-5700874-A CONJUGATED DIENE/VINYLAROMATIC HYDROCARBON COPOLYMER MODIFIED WITH ALKOXYSILANE BRIDGESTONE CORPORATION (JP) 1997-12-23 US disclosed
US-5670257-A HYDROLYZING AND CONDENSING ORGANOSILICON COMPOUND; HEAT TREATMENT; SPACERS FOR LIQUID CRYSTAL DISPLAY; NONFRACTURING NIPPON SHOKUBAI CO., LTD. (JP) 1997-09-23 US disclosed
US-5662961-A Method for forming a protective coating film on electronic parts and devices TOKYO OHKA KOGYO CO., LTD. (JP) 1997-09-02 US disclosed
US-5580619-A LIQUID CRYSTAL DISPLAY NIPPON SHOKUBAI CO., LTD. (JP) 1996-12-03 US disclosed
US-5520952-A Method for forming a protective coating film on electronic parts and devices TOKYO OHKA KOGYO CO., LTD. (JP) 1996-05-28 US disclosed
US-5503932-A SPACERS FOR LIQUID CRYSTAL DISPLAYS REQUIRING UNIFORM GAP DISTANCE BETWEEN MEMBERS; RESILIENCE NIPPON SHOKUBAI CO., LTD. (JP) 1996-04-02 US disclosed
EP-0653663-A1 Organic-inorganic composite particles and production process therefor NIPPON SHOKUBAI CO., LTD. (JP) 1995-05-17 EP disclosed