Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL5160347

CC(=O)C(C)(C)c1ccccc1.N

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 1/20 0.61
KMT2A Q03164 1/20 0.61
CYP2C19 P33261 1/20 0.48
HIF1A Q16665 1/20 0.48
HDAC3 O15379 2/20 0.47
HDAC4 P56524 2/20 0.47
HDAC1 Q13547 2/20 0.47
HDAC7 Q8WUI4 2/20 0.47
HDAC2 Q92769 2/20 0.47
HDAC10 Q969S8 2/20 0.47
HDAC11 Q96DB2 2/20 0.47
HDAC8 Q9BY41 2/20 0.47
HDAC6 Q9UBN7 2/20 0.47
HDAC9 Q9UKV0 2/20 0.47
HDAC5 Q9UQL6 2/20 0.47
KCNN4 O15554 1/20 0.43
ALDH1A1 P00352 2/20 0.43
CYP1A2 P05177 2/20 0.43
ALOX15 P16050 1/20 0.43
ESR1 P03372 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrogen Peroxide SCHEMBL1652477 0.98 MAPT (0.64) MAPTKMT2ACYP2C19HIF1AHDAC3
SCHEMBL343807 0.98 MAPT (0.64) MAPTKMT2ACYP2C19HIF1AHDAC3
SCHEMBL9293066 0.85 KMT2A (0.46) MAPTKMT2ACYP2C19HIF1AHDAC3
SCHEMBL25049822 0.80 MAPT (0.67) MAPTKMT2ACYP2C19HIF1AHDAC3
SCHEMBL6571 0.80 MAPT (0.67) MAPTKMT2ACYP2C19HIF1AHDAC3
SCHEMBL13221161 0.78 MAPT (0.52) MAPTKMT2ACYP2C19HIF1AHDAC3
SCHEMBL29033303 0.78 MAPT (0.64) MAPTKMT2ACYP2C19HIF1AHDAC3
Methyl Alcohol SCHEMBL5282426 0.78 MAPT (0.64) MAPTKMT2ACYP2C19HIF1AHDAC3
SCHEMBL6968554 0.78 MAPT (0.64) MAPTKMT2ACYP2C19HIF1AHDAC3
SCHEMBL6357425 0.78 HDAC3 (0.59) MAPTKMT2ACYP2C19HIF1AHDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1560833-B1 PREPARATION OF CODEINE FROM MORPHINE MALLINCKRODT INTERNAT CORP (US) 2007-03-14 EP claimed
EP-1560833-A2 PREPARATION OF CODEINE FROM MORPHINE Mallinckrodt International Corporation (US) 2005-08-10 EP claimed
WO-2004037826-A2 PREPARATION OF CODEINE FROM MORPHINE MALLINCKRODT INC. (US) 2004-05-06 WO claimed
US-6579985-B1 Preparation of codeine from morphine MALLINCKRODT INC. 2003-06-17 US claimed
EP-1560833-B1 PREPARATION OF CODEINE FROM MORPHINE MALLINCKRODT INTERNAT CORP (US) 2007-03-14 EP disclosed
EP-1560833-A2 PREPARATION OF CODEINE FROM MORPHINE Mallinckrodt International Corporation (US) 2005-08-10 EP disclosed
WO-2004037826-A2 PREPARATION OF CODEINE FROM MORPHINE MALLINCKRODT INC. (US) 2004-05-06 WO disclosed
US-6579985-B1 Preparation of codeine from morphine MALLINCKRODT INC. 2003-06-17 US disclosed
EP-0268710-A1 Improved process for the preparation of codeine from morphine Council of Scientific and Industrial Research (IN) 1988-06-01 EP disclosed