Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 7/20 | 0.67 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NMT1 | P30419 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3563355 | 0.88 | SLC16A3 (0.61) | SLC16A3HDAC3NCOR2HDAC1HDAC2 | |
| SCHEMBL3555109 | 0.83 | SLC16A3 (0.57) | SLC16A3HDAC3NCOR2HDAC1MEN1 | |
| SCHEMBL3554361 | 0.82 | SLC16A3 (1.00) | SLC16A3HDAC3NCOR2HDAC1HDAC2 | |
| SCHEMBL3554743 | 0.80 | SLC16A3 (0.72) | SLC16A3HDAC3NCOR2HDAC1HDAC2 | |
| SCHEMBL3556284 | 0.78 | SLC16A3 (0.70) | SLC16A3HDAC3NCOR2HDAC1HDAC2 | |
| SCHEMBL3557587 | 0.77 | HDAC3 (0.73) | SLC16A3HDAC3NCOR2HDAC1HDAC2 | |
| SCHEMBL3562788 | 0.76 | SLC16A3 (0.88) | SLC16A3MEN1KMT2AGAAALDH1A1 | |
| SCHEMBL3551157 | 0.75 | SLC16A3 (0.64) | SLC16A3HDAC3NCOR2HDAC1HDAC2 | |
| SCHEMBL3554928 | 0.75 | SLC16A3 (0.70) | SLC16A3NMT1 | |
| SCHEMBL3561861 | 0.75 | SLC16A3 (0.70) | SLC16A3HDAC3NCOR2HDAC1HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761486-A1 | PHENYLCARBOXYLIC ACID DERIVATIVES AND USE THEREOF FOR THE TREATMENT OF DIABETES | Merck Patent GmbH (DE) | 2007-03-14 | — | — | EP | disclosed |
| WO-2006000288-A1 | PHENYLCARBOXYLIC ACID DERIVATIVES AND USE THEREOF FOR THE TREATMENT OF DIABETES | MERCK PATENT GMBH (DE) | 2006-01-05 | — | — | WO | disclosed |