Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 20/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5162697 | 0.89 | TACR1 (0.55) | TACR1 | |
| SCHEMBL5159242 | 0.82 | TACR1 (0.51) | TACR1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5159599 | 0.81 | TACR1 (0.51) | TACR1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5156785 | 0.80 | TACR1 (0.47) | TACR1 | |
| SCHEMBL5159012 | 0.80 | TACR1 (0.56) | TACR1 | |
| SCHEMBL5158626 | 0.80 | TACR1 (0.49) | TACR1 | |
| SCHEMBL5158554 | 0.80 | TACR1 (0.45) | TACR1CYP3A4CYP2D6 | |
| SCHEMBL5159563 | 0.80 | TACR1 (0.52) | TACR1 | |
| SCHEMBL5159571 | 0.79 | TACR1 (0.54) | TACR1 | |
| SCHEMBL5162264 | 0.79 | TACR1 (0.46) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1748984-A1 | PIPERIDINE DERIVATIVES AS NK1 AND NK3 ANTAGONISTS | Pfizer Products Inc. (US) | 2007-02-07 | — | — | EP | claimed |
| WO-2005110987-A1 | PIPERIDINE DERIVATIVES AS NK1 AND NK3 ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2005-11-24 | — | — | WO | claimed |