Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.30 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5057236 | 1.00 | KMT2A (0.31) | KMT2AALDH1A1TRIM24TRIM33 | |
| SCHEMBL231283 | 0.97 | — | — | |
| SCHEMBL7340365 | 0.93 | KMT2A (0.36) | KMT2AALDH1A1TRIM24TRIM33 | |
| SCHEMBL61818 | 0.93 | KMT2A (0.36) | KMT2AALDH1A1TRIM24TRIM33 | |
| SCHEMBL625943 | 0.93 | KMT2A (0.36) | KMT2AALDH1A1TRIM24TRIM33 | |
| SCHEMBL25327994 | 0.93 | KMT2A (0.36) | KMT2AALDH1A1TRIM24TRIM33 | |
| SCHEMBL9956415 | 0.93 | KMT2A (0.36) | KMT2AALDH1A1TRIM24TRIM33 | |
| SCHEMBL11594630 | 0.93 | KMT2A (0.36) | KMT2AALDH1A1TRIM24TRIM33 | |
| SCHEMBL542776 | 0.93 | KMT2A (0.36) | KMT2AALDH1A1TRIM24TRIM33 | |
| SCHEMBL13858690 | 0.93 | KMT2A (0.36) | KMT2AALDH1A1TRIM24TRIM33 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1751088-A1 | OXO-SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES | Grünenthal GmbH (DE) | 2007-02-14 | — | — | EP | claimed |
| WO-2005110970-A1 | OXO-SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES | Grünenthal GmbH (DE) | 2005-11-24 | — | — | WO | claimed |
| CN-115557933-A | Bruton tyrosine kinase and mutant degradation agent, composition and application thereof | 杭州和正医药有限公司 | 2023-01-03 | — | — | CN | disclosed |
| EP-1751088-A1 | OXO-SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES | Grünenthal GmbH (DE) | 2007-02-14 | — | — | EP | disclosed |
| WO-2005110970-A1 | OXO-SUBSTITUTED CYCLOHEXYL-1,4-DIAMINE DERIVATIVES | Grünenthal GmbH (DE) | 2005-11-24 | — | — | WO | disclosed |