Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 16/20 | 0.61 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | SCN1A | P35498 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.50 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3271106 | 0.98 | HRH3 (0.64) | HRH3KCNH2MAPK1ALDH1A1CYP1A2 | |
| SCHEMBL3277540 | 0.97 | HRH3 (0.66) | HRH3KCNH2MAPK1ALDH1A1CYP1A2 | |
| Hydrochloric Acid SCHEMBL3271362 | 0.96 | HRH3 (0.65) | HRH3KCNH2MAPK1ALDH1A1CYP1A2 | |
| SCHEMBL3271955 | 0.94 | HRH3 (0.60) | HRH3KCNH2MAPK1ALDH1A1CYP1A2 | |
| SCHEMBL3272214 | 0.92 | HRH3 (0.57) | HRH3KCNH2MAPK1ALDH1A1CYP1A2 | |
| SCHEMBL3270444 | 0.92 | HRH3 (0.60) | HRH3KCNH2MAPK1ALDH1A1CYP1A2 | |
| SCHEMBL3276000 | 0.92 | HRH3 (0.56) | HRH3 | |
| Methylamine SCHEMBL5161945 | 0.91 | HRH3 (0.55) | HRH3KCNH2MAPK1ALDH1A1CYP1A2 | |
| SCHEMBL3272560 | 0.90 | HRH3 (0.55) | HRH3KCNH2MAPK1ALDH1A1CYP1A2 | |
| SCHEMBL3272967 | 0.90 | HRH3 (0.54) | HRH3KCNH2MAPK1ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1747210-A1 | 3- OR 4-MONOSUBSTITUTED PHENOL AND THIOPHENOL DERIVATIVES USEFUL AS H3 LIGANDS | Warner-Lambert Company LLC (US) | 2007-01-31 | — | — | EP | disclosed |
| WO-2005108384-A1 | 3- OR 4-MONOSUBSTITUTED PHENOL AND THIOPHENOL DERIVATIVES USEFUL AS H3 LIGANDS | WARNER-LAMBERT COMPANY LLC (US) | 2005-11-17 | — | — | WO | disclosed |