SCHEMBL516147

SCHEMBL516147

Cc1cc(O)ccc1C1(c2ccc(O)cc2C)c2ccccc2-c2ccccc21

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.58
ALOX12 P18054 2/20 0.58
LMNA P02545 1/20 0.58
POLB P06746 1/20 0.58
NPSR1 Q6W5P4 1/20 0.58
GPR55 Q9Y2T6 1/20 0.58
ESR2 Q92731 9/20 0.53
ESR1 P03372 8/20 0.53
PDK2 Q15119 5/20 0.49
MEN1 O00255 2/20 0.40
KMT2A Q03164 2/20 0.40
HPGD P15428 1/20 0.40
CYP2C19 P33261 1/20 0.40
HTT P42858 1/20 0.40
RECQL P46063 1/20 0.40
BLM P54132 1/20 0.40
SMAD3 P84022 1/20 0.40
PRMT1 Q99873 1/20 0.40
ACE2 Q9BYF1 1/20 0.40
FTO Q9C0B1 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29480886 1.00 MAPT (0.58) MAPTALOX12LMNAPOLBNPSR1
SCHEMBL9228828 0.90 ESR2 (0.55) MAPTALOX12LMNAPOLBNPSR1
SCHEMBL5437701 0.85 ESR2 (0.53) MAPTALOX12LMNAPOLBNPSR1
SCHEMBL15845412 0.84 PDK2 (0.65) MAPTALOX12LMNAPOLBNPSR1
SCHEMBL27392595 0.84 PDK2 (0.65) MAPTALOX12LMNAPOLBNPSR1
SCHEMBL6292675 0.84 PDK2 (0.65) MAPTALOX12LMNAPOLBNPSR1
SCHEMBL12281176 0.81 PDK2 (0.51) MAPTALOX12LMNAPOLBNPSR1
SCHEMBL21547754 0.81 ESR2 (0.53) MAPTALOX12LMNAPOLBNPSR1
SCHEMBL21391631 0.80 PDK2 (0.59) MAPTALOX12LMNAPOLBNPSR1
SCHEMBL20941772 0.80 PDK2 (0.59) MAPTALOX12LMNAPOLBNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 245 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8710157-B2 Contact lens material MENICON CO., LTD. (JP) 2014-04-29 US claimed
EP-2455797-B1 MATERIAL FOR CONTACT LENS MENICON CO LTD (JP) 2013-12-25 EP claimed
US-8501878-B2 Method for producing polycarbonate material having excellent solubility and affinity, and contact lens material comprising the same MENICON CO., LTD. (JP) 2013-08-06 US claimed
EP-2455797-A1 MATERIAL FOR CONTACT LENS Menicon Co., Ltd. (JP) 2012-05-23 EP claimed
EP-2455798-A1 PROCESS FOR PRODUCTION OF POLYCARBONATE MATERIAL HAVING EXCELLENT SOLUBILITY AND AFFINITY, AND MATERIAL FOR CONTACT LENS COMPRISING THE SAME Menicon Co., Ltd. (JP) 2012-05-23 EP claimed
US-20120116028-A1 METHOD FOR PRODUCING POLYCARBONATE MATERIAL HAVING EXCELLENT SOLUBILITY AND AFFINITY, AND CONTACT LENS MATERIAL COMPRISING THE SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2012-05-10 US claimed
US-20120116019-A1 CONTACT LENS MATERIAL MENICON CO., LTD. (JP) 2012-05-10 US claimed
US-8173720-B2 Transparent gel and contact lense from the same MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2012-05-08 US claimed
EP-1840167-B1 TRANSPARENT GEL AND CONTACT LENS COMPRISING THE SAME MENICON CO LTD (JP) 2010-10-06 EP claimed
US-20090012205-A1 TRANSPARENT GEL AND CONTACT LENSE FROM THE SAME MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2009-01-08 US claimed
EP-1223184-B1 Polycarbonate resin MITSUBISHI GAS CHEMICAL CO (JP) 2005-03-30 EP claimed
EP-1138714-B1 Polycarbonate resin and optical article used the same MITSUBISHI GAS CHEMICAL CO (JP) 2005-02-23 EP claimed
US-6630562-B2 Radiation and wear resistant molding materials; weatherproofing; mixture with polysiloxane MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2003-10-07 US claimed
US-20020132959-A1 Polycarbonate resin MITSUBISHI GAS CHEMICAL COMPANY, INC. 2002-09-19 US claimed
EP-1223184-A1 Polycarbonate resin MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2002-07-17 EP claimed
US-6340737-B2 COPOLYCARBONATE OF A 9,9-BIS(HYDROXYPHENYL)FLUORENE COMPOUND, A POLYSILOXANE ENDCAPPED WITH A HYDROXYPHENYL GROUP, AND A PHENOLIC DIOL SUCH AS BISPHENOL A; REDUCED OBLIQUE INCIDENCE BIREFRINGENCE, MOLDABILITY, GOOD TRANSPARENCY MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2002-01-22 US claimed
US-20010039313-A1 Polycarbonate resin and optical article used the same MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2001-11-08 US claimed
EP-1138714-A2 Polycarbonate resin and optical article used the same MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2001-10-04 EP claimed
US-12637540-B2 Resin produced by polycondensation, and resin composition MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2026-05-26 US disclosed
US-5124307-A Electron donating dye precursor, fluorene bisphenol, binder; fade-resistant images APPLETON PAPERS INC. (US) 1992-06-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12637540-B2 Resin produced by polycondensation, and resin composition TAF1, TAF5, PUF60 MAPT 1854/4885ALOX12 1254/4885LMNA 3115/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.