SCHEMBL5161583

SCHEMBL5161583

C[Si](C)(O)CCC[Si](O[Si](C)(C)CCCOS(C)(=O)=O)(O[Si](C)(C)CCCOS(C)(=O)=O)O[Si](C)(C)CCCOS(C)(=O)=O

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.42
USP2 O75604 1/20 0.42
ALDH1A1 P00352 1/20 0.42
LMNA P02545 1/20 0.42
MMP9 P14780 1/20 0.42
ALOX15 P16050 1/20 0.42
TSHR P16473 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3164150 0.87 KDM4E (0.45) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL5161576 0.87 KDM4E (0.45) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL3179090 0.87 KDM4E (0.45) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL6413911 0.80 KDM4E (0.38) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL4871783 0.78 KDM4E (0.54) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL5161620 0.77
SCHEMBL5161785 0.74
SCHEMBL5159942 0.73
SCHEMBL14194111 0.71 KDM4E (0.54) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL2057502 0.69 USP2 (0.64) KDM4EUSP2ALDH1A1LMNAMMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1453888-B1 SACCHARIDE RESIDUE-FUNCTIONAL ORGANOPOLYCARBOSILOXANES AND METHOD FOR THE PREPARATION THEREOF DOW CORNING TORAY CO LTD (JP) 2007-03-14 EP disclosed
EP-1453888-A1 SACCHARIDE RESIDUE-FUNCTIONAL ORGANOPOLYCARBOSILOXANES AND METHOD FOR THE PREPARATION THEREOF Dow Corning Toray Co., Ltd. (JP) 2004-09-08 EP disclosed
WO-2003042284-A1 SACCHARIDE RESIDUE-FUNCTIONAL ORGANOPOLYCARBOSILOXANES AND METHOD FOR THE PREPARATION THEREOF DOW CORNING TORAY SILICONE CO., LTD. (JP) 2003-05-22 WO disclosed