SCHEMBL5161809

SCHEMBL5161809

CO[Si](CCCC(=CC(=O)O)C(=CC(=O)O)CCC[Si](OC)(OC)OC)(OC)OC

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.33
TSHR P16473 1/20 0.33
LMNA P02545 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28319856 0.93 KDM4E (0.39) KDM4ETSHR
SCHEMBL1759715 0.93 KDM4E (0.39) KDM4ETSHR
SCHEMBL1759711 0.93 KDM4E (0.39) KDM4ETSHR
SCHEMBL11196326 0.85
SCHEMBL7795238 0.82 TSHR (0.35) TSHR
SCHEMBL18984973 0.80 APEX1 (0.33)
SCHEMBL700717 0.77 TSHR (0.48) TSHRLMNAALDH1A1
SCHEMBL8855803 0.75 KDM4E (0.37) KDM4ETSHR
SCHEMBL10589959 0.75 KDM4E (0.37) KDM4ETSHR
SCHEMBL8855778 0.75 KDM4E (0.37) KDM4ETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1138738-B1 Curable silicone adhesive compositions GEN ELECTRIC (US) 2005-07-20 EP claimed
EP-1138738-A2 Curable silicone adhesive compositions GENERAL ELECTRIC COMPANY (US) 2001-10-04 EP claimed
US-6296944-B1 SILICONES ROOM VULCANATION FOR ADHESIVES FOR METALS GENERAL ELECTRIC COMPANY 2001-10-02 US claimed
EP-1207188-B1 Curable silicone adhesive compositions GEN ELECTRIC (US) 2007-03-07 EP disclosed
EP-1138738-B1 Curable silicone adhesive compositions GEN ELECTRIC (US) 2005-07-20 EP disclosed
US-6447922-B1 BIS(TRIALKOXYSILYLALKYL)SUCCINATE ADHESION PROMOTER, A VINYL-CONTAINING POLYDIORGANOSILOXANE, A HYDROGEN-CONTAINING POLYSILOXANE, HYDROSILYLATION CATALYST; ROOM TEMPERATURE VULCANIZABLE GENERAL ELECTRIC COMPANY 2002-09-10 US disclosed
EP-1207188-A2 Curable silicone adhesive compositions GENERAL ELECTRIC COMPANY (US) 2002-05-22 EP disclosed
EP-1138738-A2 Curable silicone adhesive compositions GENERAL ELECTRIC COMPANY (US) 2001-10-04 EP disclosed
US-6296944-B1 SILICONES ROOM VULCANATION FOR ADHESIVES FOR METALS GENERAL ELECTRIC COMPANY 2001-10-02 US disclosed