⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrogen Sulfide SCHEMBL28130279 | 0.96 | — | — | |
| Hydrochloric Acid SCHEMBL28050094 | 0.96 | — | — | |
| Phosphine SCHEMBL28148577 | 0.96 | — | — | |
| Pyridine SCHEMBL28227771 | 0.84 | NAPRT (0.53) | — | |
| Formic Acid Methyl Ester SCHEMBL28220770 | 0.76 | TRIM24 (0.39) | — | |
| SCHEMBL7968855 | 0.65 | KDM4E (0.50) | — | |
| SCHEMBL6536 | 0.65 | — | — | |
| SCHEMBL18660494 | 0.65 | — | — | |
| SCHEMBL3361754 | 0.65 | — | — | |
| SCHEMBL2320499 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 4617 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250361228-A1 | PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF SOLUBLE GUANYLATE CYCLASE STIMULATORS | CYCLERION THERAPEUTICS INC (US) | 2025-11-27 | — | — | US | claimed |
| EP-4570797-A2 | NOVEL PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF SOLUBLE GUANYLATE CYCLASE STIMULATORS | Cyclerion Therapeutics, Inc. (US) | 2025-06-18 | — | — | EP | claimed |
| CN-120118030-A | Synthesis method of pyrifos-bromine | 华中药业股份有限公司 | 2025-06-10 | — | — | CN | claimed |
| CN-119462520-A | Preparation method of substituted benzoate derivative | 上海皓元医药股份有限公司 | 2025-02-18 | — | — | CN | claimed |
| US-12030874-B2 | Processes and intermediates for the preparation of soluble guanylate cyclase stimulators | CYCLERION THERAPEUTICS, INC. (US) | 2024-07-09 | — | — | US | claimed |
| CN-118221665-A | Methods and intermediates for preparing soluble guanylate cyclase stimulators | 赛克里翁治疗有限公司 | 2024-06-21 | — | — | CN | claimed |
| CN-118184645-A | Methods and intermediates for preparing soluble guanylate cyclase stimulators | 赛克里翁治疗有限公司 | 2024-06-14 | — | — | CN | claimed |
| CN-118146210-A | Organic molecular additive and preparation method and application thereof | 正泰新能科技股份有限公司 | 2024-06-07 | — | — | CN | claimed |
| CN-118063720-A | Ni-loaded covalent organic framework material and preparation method and application thereof | 上海师范大学 | 2024-05-24 | — | — | CN | claimed |
| CN-111902410-B | Methods and intermediates for preparing soluble guanylate cyclase stimulators | 赛克里翁治疗有限公司 | 2024-04-19 | — | — | CN | claimed |
| EP-0725641-B1 | NOVEL INHIBITORS OF URIDINE PHOSPHORYLASE (UrdPase) AND DIHYDROURACIL DEHYDROGENASE (DHUDase) | EL KOUNI MAHMOUD H (US) | 2000-12-13 | — | — | EP | claimed |
| EP-0522964-B1 | Compositions to arrest hair loss and to induce and stimulate hair growth based on 2,4-diamino-pyrimidin-3-oxide derivatives | OREAL (FR) | 2000-10-04 | — | — | EP | claimed |
| CN-1194647-A | Pyrrolopyrimidines and processes for preparation thereof | NOVARTIS CO (CH) | 1998-09-30 | — | — | CN | claimed |
| EP-0725641-A4 | — | — | 1996-09-04 | — | — | EP | claimed |
| EP-0557291-B1 | PYRIDIL-PYRIMIDINE DERIVATIVES AS FUNGICIDAL COMPOUNDS | ZENECA LTD (GB) | 1996-08-14 | — | — | EP | claimed |
| EP-0725641-A1 | NOVEL ENZYME INHIBITORS, THEIR SYNTHESIS, AND METHODS FOR USE | El Kouni, Mahmoud H. (US) | 1996-08-14 | — | — | EP | claimed |
| WO-1995012400-A1 | NOVEL ENZYME INHIBITORS, THEIR SYNTHESIS, AND METHODS FOR USE | UAB RESEARCH FOUNDATION (US) | 1995-05-11 | — | — | WO | claimed |
| EP-0557291-A1 | PYRIDIL-PYRIMIDINE DERIVATIVES AS FUNGICIDAL COMPOUNDS. | ICI PLC (GB) | 1993-09-01 | — | — | EP | claimed |
| US-5130380-A | Conductive polymers | CAREW EVAN B (US) | 1992-07-14 | — | — | US | claimed |
| WO-1992008714-A1 | PYRIDIL-PYRIMIDINE DERIVATIVES AS FUNGICIDAL COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-05-29 | — | — | WO | claimed |