Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 10/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.42 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5162168 | 0.92 | HDAC3 (0.42) | SLC16A3HDAC3NCOR2HDAC1HDAC2 | |
| SCHEMBL3553428 | 0.91 | SLC16A3 (0.57) | SLC16A3HDAC3NCOR2HDAC1METAP2 | |
| SCHEMBL3556313 | 0.88 | SLC16A3 (0.64) | SLC16A3TAS2R14 | |
| SCHEMBL3555485 | 0.86 | SLC16A3 (0.64) | SLC16A3HDAC3NCOR2HDAC1METAP2 | |
| SCHEMBL3559260 | 0.83 | SLC16A3 (0.60) | SLC16A3HDAC3NCOR2HDAC1METAP2 | |
| SCHEMBL3563137 | 0.83 | SLC16A3 (0.71) | SLC16A3HDAC3NCOR2HDAC1TAS2R14 | |
| SCHEMBL3552022 | 0.82 | SLC16A3 (0.63) | SLC16A3HDAC3NCOR2HDAC1METAP2 | |
| SCHEMBL3561760 | 0.80 | SLC16A3 (0.63) | SLC16A3HDAC3NCOR2HDAC1METAP2 | |
| SCHEMBL3563493 | 0.80 | SLC16A3 (0.63) | SLC16A3HDAC3NCOR2HDAC1TAS2R14 | |
| SCHEMBL3564319 | 0.80 | SLC16A3 (0.63) | SLC16A3HDAC3NCOR2HDAC1METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761486-A1 | PHENYLCARBOXYLIC ACID DERIVATIVES AND USE THEREOF FOR THE TREATMENT OF DIABETES | Merck Patent GmbH (DE) | 2007-03-14 | — | — | EP | claimed |
| WO-2006000288-A1 | PHENYLCARBOXYLIC ACID DERIVATIVES AND USE THEREOF FOR THE TREATMENT OF DIABETES | MERCK PATENT GMBH (DE) | 2006-01-05 | — | — | WO | claimed |