SCHEMBL516294

SCHEMBL516294

C=C(C)C(=O)Nc1ccccc1[N+](=O)[O-]

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.61
MEN1 O00255 2/20 0.61
KCNMA1 Q12791 1/20 0.54
PDK1 Q15118 1/20 0.54
PDK2 Q15119 1/20 0.54
PDK3 Q15120 1/20 0.54
PDK4 Q16654 1/20 0.54
PHGDH O43175 1/20 0.52
ALDH1A1 P00352 2/20 0.52
LMNA P02545 2/20 0.52
RAB9A P51151 2/20 0.51
GAA P10253 1/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2C9 P11712 1/20 0.51
CYP2C19 P33261 1/20 0.51
NPSR1 Q6W5P4 1/20 0.51
TP53 P04637 1/20 0.51
NPC1 O15118 2/20 0.50
MAPT P10636 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2766319 0.86 POLB (0.62) KMT2AMEN1ALDH1A1LMNARAB9A
SCHEMBL6857920 0.86 KMT2A (0.73) KMT2AMEN1KCNMA1PDK1PDK2
SCHEMBL31598592 0.85 KMT2A (0.63) KMT2AMEN1KCNMA1PDK1PDK2
SCHEMBL6854893 0.83 KMT2A (0.65) KMT2AMEN1KCNMA1PDK1PDK2
SCHEMBL29740651 0.83 KMT2A (0.69) KMT2AMEN1KCNMA1PDK1PDK2
SCHEMBL733777 0.83 KMT2A (0.69) KMT2AMEN1KCNMA1PDK1PDK2
Fluoride SCHEMBL28083677 0.81 KMT2A (0.67) KMT2AMEN1KCNMA1PDK1PDK2
SCHEMBL8925968 0.81 KMT2A (0.67) KMT2AMEN1KCNMA1PDK1PDK2
SCHEMBL6418936 0.80 NPC1 (0.59) ALDH1A1RAB9AGAANPC1MAPT
SCHEMBL11459180 0.80 MEN1 (0.65) KMT2AMEN1KCNMA1PDK1PDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 260 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6423458-B1 None US disclosed
WO-2025045206-A1 PYRUVIC ACID (HETERO)ARYL THIOESTER COMPOUNDS FOR LED PHOTOPOLYMERIZATION, PREPARATION THEREFOR AND USE THEREOF 湖北固润科技股份有限公司 2025-03-06 WO disclosed
CN-112154149-B New vinylphosphines and photoinitiators obtainable therefrom 汉斯约尔格·格吕茨马赫 2025-02-21 CN disclosed
CN-115504896-B Acrylic formate compound for LED photopolymerization, preparation method and application thereof 湖北固润科技股份有限公司 2024-05-07 CN disclosed
WO-2024078413-A1 ACRYLOYL FORMATE COMPOUND FOR LED PHOTOPOLYMERIZATION, AND PREPARATION METHOD THEREFOR AND USE THEREOF 湖北固润科技股份有限公司 2024-04-18 WO disclosed
CN-117142994-A Amphiphilic polyether alpha-ketone (hetero) arylthioester compound for LED photopolymerization and preparation and application thereof 湖北固润科技股份有限公司 2023-12-01 CN disclosed
CN-117142995-A Pyruvic acid (hetero) arylthioester compound for LED photopolymerization and preparation and application thereof 湖北固润科技股份有限公司 2023-12-01 CN disclosed
CN-115504896-A Acryloyl formate compound for LED photopolymerization, and preparation method and application thereof 湖北固润科技股份有限公司 2022-12-23 CN disclosed
CN-114181249-A Derivatives of bisacylphosphinic acids, their preparation and their use as photoinitiators IGM集团公司 2022-03-15 CN disclosed
CN-112154149-A Novel vinylphosphines and photoinitiators obtainable therefrom 汉斯约尔格·格吕茨马赫 2020-12-29 CN disclosed
EP-0992850-A2 Planographic printing original plate FUJI PHOTO FILM CO., LTD. (JP) 2000-04-12 EP disclosed
EP-0965887-A1 Photosensitive lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 1999-12-22 EP disclosed
EP-0722121-B1 Photosensitive planographic printing plate FUJI PHOTO FILM CO LTD (JP) 1999-04-28 EP disclosed
EP-0907107-A2 Package of photosensitive planographic printing plates and photosensitive planographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 1999-04-07 EP disclosed
EP-0904954-A2 Positive working photosensitive lithographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 1999-03-31 EP disclosed
US-5837345-A Support for lithographic printing plate, process for the preparation thereof and electrochemical roughening apparatus FUJI PHOTO FILM CO., LTD. (JP) 1998-11-17 US disclosed
EP-0730979-A2 Support for lithographic printing plate, process for the preparation thereof and electrochemical roughening apparatus FUJI PHOTO FILM CO., LTD. (JP) 1996-09-11 EP disclosed
EP-0722121-A1 Photosensitive planographic printing plate FUJI PHOTO FILM CO., LTD. (JP) 1996-07-17 EP disclosed
US-4873166-A Liquid developer for electrophotography MITSUBISHI PAPER MILLS, LTD. (JP) 1989-10-10 US disclosed
US-4002673-A GROUP VIII METAL SULFIDE AS HYDROGENATION CATALYST BAYER AKTIENGESELLSCHAFT (DT) 1977-01-11 US disclosed