Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 7/20 | 0.57 |
| ▸ | MPI | P34949 | 6/20 | 0.57 |
| ▸ | XBP1 | P17861 | 5/20 | 0.57 |
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | S1PR2 | O95136 | 3/20 | 0.57 |
| ▸ | PKM | P14618 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.54 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5160707 | 0.82 | MAPT (0.69) | MAPTALDH1A1NPSR1MPIXBP1 | |
| SCHEMBL15299765 | 0.82 | MAPT (0.69) | MAPTALDH1A1NPSR1MPIXBP1 | |
| SCHEMBL5161482 | 0.82 | MAPT (0.57) | MAPTALDH1A1NPSR1MPIXBP1 | |
| SCHEMBL5162997 | 0.82 | MAPT (0.57) | MAPTALDH1A1NPSR1MPIXBP1 | |
| SCHEMBL15299805 | 0.82 | MAPT (0.69) | MAPTALDH1A1NPSR1MPIXBP1 | |
| SCHEMBL5162994 | 0.79 | MAPT (0.55) | MAPTALDH1A1NPSR1MPIXBP1 | |
| SCHEMBL5163602 | 0.76 | MAPT (0.63) | MAPTALDH1A1NPSR1MPIXBP1 | |
| SCHEMBL5161476 | 0.76 | MAPT (0.33) | MAPTALDH1A1NPSR1MPIXBP1 | |
| SCHEMBL2045041 | 0.75 | MAPT (0.59) | MAPTALDH1A1NPSR1MPIXBP1 | |
| SCHEMBL5161441 | 0.75 | MAPT (0.70) | MAPTALDH1A1NPSR1MPIXBP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1399114-B1 | AGENT CONTAINING QUINONIMINE DERIVATIVES AND USED TO COLOUR KERATIN FIBRES, AND ASSOCIATED METHOD | WELLA AG (DE) | 2007-03-28 | — | — | EP | claimed |
| US-7056349-B2 | Agent containing quinonimine derivatives and used to color keratin fibres, and associated method | WELLA AG (DE) | 2006-06-06 | — | — | US | claimed |
| US-20030182736-A1 | Agent containing quinonimine derivatives and used to colour keratin fibres, and associated method | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2003-10-02 | — | — | US | claimed |
| EP-1399114-B1 | AGENT CONTAINING QUINONIMINE DERIVATIVES AND USED TO COLOUR KERATIN FIBRES, AND ASSOCIATED METHOD | WELLA AG (DE) | 2007-03-28 | — | — | EP | disclosed |
| US-7056349-B2 | Agent containing quinonimine derivatives and used to color keratin fibres, and associated method | WELLA AG (DE) | 2006-06-06 | — | — | US | disclosed |
| EP-1399114-A1 | AGENT CONTAINING QUINONIMINE DERIVATIVES AND USED TO COLOUR KERATIN FIBRES, AND ASSOCIATED METHOD | Wella Aktiengesellschaft (DE) | 2004-03-24 | — | — | EP | disclosed |
| US-20030182736-A1 | Agent containing quinonimine derivatives and used to colour keratin fibres, and associated method | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2003-10-02 | — | — | US | disclosed |
| WO-2002102336-A1 | AGENT CONTAINING QUINONIMINE DERIVATIVES AND USED TO COLOUR KERATIN FIBRES, AND ASSOCIATED METHOD | WELLA AKTIENGESELLSCHAFT (DE) | 2002-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030182736-A1 | Agent containing quinonimine derivatives and used to colour keratin fibres, and associated method | KRT18, MKI67, F12 | MAPT 661/4885ALDH1A1 380/4885NPSR1 2334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.