Hexadecane

Hexadecane

SCHEMBL5163754

Br.C=C(C)C(=O)OCCN(C)C.CCCCCCCCCCCCCCCC

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4

The experimentally established mechanism targets of Hexadecane. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM2 known ✓ P08172 1/20 0.43
CHRM3 known ✓ P20309 1/20 0.43
ACHE known ✓ P22303 1/20 0.40
SLC6A3 known ✓ Q01959 1/20 0.40
SIGMAR1 known ✓ Q99720 1/20 0.40
TSHR P16473 3/20 0.69
DNM1 Q05193 6/20 0.58
THRB P10828 3/20 0.47
CHRM4 P08173 1/20 0.43
CHRM5 P08912 1/20 0.43
CHRM1 P11229 1/20 0.43
CHRNB2 P17787 1/20 0.43
CHRNA4 P43681 1/20 0.43
NAAA Q02083 1/20 0.42
LMNA P02545 2/20 0.40
CYP1A2 P05177 1/20 0.40
MAOA P21397 1/20 0.40
CNR1 P21554 1/20 0.40
DRD4 P21917 1/20 0.40
HRH2 P25021 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9505548 0.95 TSHR (0.77) TSHRDNM1THRBCHRM2CHRM4
SCHEMBL10939056 0.95 TSHR (0.77) TSHRDNM1THRBCHRM2CHRM4
SCHEMBL29139797 0.95 TSHR (0.77) TSHRDNM1THRBCHRM2CHRM4
SCHEMBL9806862 0.94 TSHR (0.75) TSHRDNM1THRBCHRM2CHRM4
SCHEMBL28905711 0.93 TSHR (0.74) TSHRDNM1THRBCHRM2CHRM4
Dodecylamine SCHEMBL28732701 0.93 TSHR (0.59) TSHRDNM1THRBCHRM2CHRM4
Hexadecylamine SCHEMBL28102958 0.93 TSHR (0.59) TSHRDNM1THRBCHRM2CHRM4
Chloromethane SCHEMBL3318985 0.92 TSHR (0.73) TSHRDNM1THRBCHRM2CHRM4
SCHEMBL1704602 0.92 TSHR (0.66) TSHRDNM1THRBCHRM2CHRM4
SCHEMBL8424369 0.92 TSHR (0.66) TSHRDNM1THRBCHRM2CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1177104-B1 INKJET RECEPTOR MEDIUM HAVING A MULTI-STAGED INK MIGRATION INHIBITOR 3M INNOVATIVE PROPERTIES CO (US) 2007-03-28 EP claimed
US-6514599-B1 Highly water soluble polymer such as vinylpyrrolidone-acrylic acid-dimethylaminoethyl acrylate methylchloride terpolymer immobilizing pigment particles and dispersants 3M INNOVATIVE PROPERTIES COMPANY 2003-02-04 US claimed
EP-1177104-A1 INKJET RECEPTOR MEDIUM HAVING A MULTI-STAGED INK MIGRATION INHIBITOR 3M Innovative Properties Company (US) 2002-02-06 EP claimed
WO-2000063023-A1 INKJET RECEPTOR MEDIUM HAVING A MULTI-STAGED INK MIGRATION INHIBITOR 3M INNOVATIVE PROPERTIES COMPANY (US) 2000-10-26 WO claimed
EP-1177104-A1 INKJET RECEPTOR MEDIUM HAVING A MULTI-STAGED INK MIGRATION INHIBITOR 3M Innovative Properties Company (US) 2002-02-06 EP disclosed
WO-2000063023-A1 INKJET RECEPTOR MEDIUM HAVING A MULTI-STAGED INK MIGRATION INHIBITOR 3M INNOVATIVE PROPERTIES COMPANY (US) 2000-10-26 WO disclosed