Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A3 | O15427 | 7/20 | 0.63 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.45 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.45 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.41 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.41 |
| ▸ | ACLY | P53396 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3560831 | 0.89 | SLC16A3 (0.72) | SLC16A3AKR1C3KMT2AMEN1GAA | |
| SCHEMBL3556199 | 0.87 | SLC16A3 (0.74) | SLC16A3AKR1C3KMT2AMEN1RAB9A | |
| SCHEMBL3556646 | 0.87 | SLC16A3 (0.82) | SLC16A3AKR1C3KMT2AMEN1RAB9A | |
| SCHEMBL3553475 | 0.86 | SLC16A3 (0.71) | SLC16A3KMT2AMEN1GAARAB9A | |
| SCHEMBL3559492 | 0.83 | SLC16A3 (0.64) | SLC16A3AKR1C3KMT2AMEN1GAA | |
| SCHEMBL3560616 | 0.81 | SLC16A3 (0.72) | SLC16A3AKR1C3KMT2AMEN1RAB9A | |
| SCHEMBL3558355 | 0.81 | SLC16A3 (0.79) | SLC16A3KMT2AMEN1GAARAB9A | |
| SCHEMBL3556687 | 0.81 | SLC16A3 (0.65) | SLC16A3AKR1C3KMT2AMEN1RAB9A | |
| SCHEMBL3562402 | 0.81 | SLC16A3 (0.63) | SLC16A3KMT2AMEN1GAARAB9A | |
| SCHEMBL3564977 | 0.79 | SLC16A3 (0.67) | SLC16A3KMT2AMEN1GAARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1761486-A1 | PHENYLCARBOXYLIC ACID DERIVATIVES AND USE THEREOF FOR THE TREATMENT OF DIABETES | Merck Patent GmbH (DE) | 2007-03-14 | — | — | EP | claimed |
| WO-2006000288-A1 | PHENYLCARBOXYLIC ACID DERIVATIVES AND USE THEREOF FOR THE TREATMENT OF DIABETES | MERCK PATENT GMBH (DE) | 2006-01-05 | — | — | WO | claimed |