Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STS | P08842 | 5/20 | 0.69 |
| ▸ | CA2 | P00918 | 3/20 | 0.69 |
| ▸ | CA9 | Q16790 | 3/20 | 0.69 |
| ▸ | CA1 | P00915 | 2/20 | 0.69 |
| ▸ | ESR1 | P03372 | 5/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.59 |
| ▸ | LMNA | P02545 | 4/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.59 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.59 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.59 |
| ▸ | SHBG | P04278 | 2/20 | 0.59 |
| ▸ | PGR | P06401 | 2/20 | 0.59 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.59 |
| ▸ | AR | P10275 | 2/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.59 |
| ▸ | SNCA | P37840 | 2/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.59 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6333268 | 0.90 | STS (0.72) | STSCA2CA9CA1ESR1 | |
| SCHEMBL5167924 | 0.90 | STS (0.70) | STSCA2CA9CA1ESR1 | |
| SCHEMBL345570 | 0.89 | STS (0.71) | STSCA2CA9CA1ESR1 | |
| SCHEMBL5167108 | 0.89 | STS (0.69) | STSCA2CA9CA1ESR1 | |
| SCHEMBL5165243 | 0.82 | STS (1.00) | STSCA2CA9CA1ESR1 | |
| SCHEMBL628173 | 0.82 | STS (1.00) | STSCA2CA9CA1ESR1 | |
| Fluoroestradiol SCHEMBL5009547 | 0.81 | ESR1 (0.78) | STSESR1ESR2LMNACYP2C9 | |
| Fluoroestradiol SCHEMBL6543568 | 0.81 | ESR1 (0.78) | STSESR1ESR2LMNACYP2C9 | |
| Fluoroestradiol SCHEMBL21856652 | 0.81 | ESR1 (0.78) | STSESR1ESR2LMNACYP2C9 | |
| Fluoroestradiol SCHEMBL6543617 | 0.81 | ESR1 (0.78) | STSESR1ESR2LMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1772462-A2 | Steroid sulfamates, method for the production and use thereof | Sterix Limited (GB) | 2007-04-11 | — | — | EP | claimed |
| US-6339079-B1 | FOR THERAPY AND DIAGNOSIS OF ESTROGEN-DEPENDENT TUMORS | ID PHARMA GMBH (DE) | 2002-01-15 | — | — | US | claimed |
| EP-1772462-A2 | Steroid sulfamates, method for the production and use thereof | Sterix Limited (GB) | 2007-04-11 | — | — | EP | disclosed |
| EP-0970104-B1 | STEROID SULFAMATES, METHOD FOR THE PRODUCTION AND USE THEREOF | STERIX LTD (GB) | 2006-11-22 | — | — | EP | disclosed |
| US-6339079-B1 | FOR THERAPY AND DIAGNOSIS OF ESTROGEN-DEPENDENT TUMORS | ID PHARMA GMBH (DE) | 2002-01-15 | — | — | US | disclosed |