Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sebacic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | PPARA | Q07869 | 1/20 | 0.51 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sebacic Acid SCHEMBL5669870 | 1.00 | HDAC3 (0.58) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Azelaic Acid SCHEMBL11379325 | 1.00 | HDAC3 (0.58) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Terephthalic Acid SCHEMBL3334284 | 0.98 | HDAC3 (0.55) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Sebacic Acid SCHEMBL344766 | 0.96 | HDAC3 (0.62) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Octanedioate SCHEMBL29093966 | 0.96 | HDAC3 (0.62) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Sebacic Acid SCHEMBL6657462 | 0.96 | HDAC3 (0.62) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Isophthalic Acid SCHEMBL10399350 | 0.96 | HDAC3 (0.62) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Azelaic Acid SCHEMBL10982150 | 0.96 | HDAC3 (0.62) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Azelaic Acid SCHEMBL10980744 | 0.96 | HDAC3 (0.62) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| Sebacic Acid SCHEMBL11778565 | 0.95 | HDAC3 (0.53) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112934150-B | Biodegradable copolyester production system, preparation method and copolyester | 中国纺织科学研究院有限公司 | 2023-03-21 | — | — | CN | disclosed |
| CN-112794996-B | Preparation system and preparation method of biodegradable copolyester and copolyester thereof | 中国纺织科学研究院有限公司 | 2022-08-23 | — | — | CN | disclosed |
| CN-112934150-A | Biodegradable copolyester production system, preparation method and copolyester | 中国纺织科学研究院有限公司 | 2021-06-11 | — | — | CN | disclosed |
| CN-112794996-A | Preparation system and preparation method of biodegradable copolyester and copolyester thereof | 中国纺织科学研究院有限公司 | 2021-05-14 | — | — | CN | disclosed |
| EP-1293355-B1 | Thermal transfer film, thermal transfer recording medium, and method for image formation using the same | DAINIPPON PRINTING CO LTD (JP) | 2007-04-04 | — | — | EP | disclosed |