Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 7/20 | 0.76 |
| ▸ | OPRM1 | P35372 | 6/20 | 0.76 |
| ▸ | HTR2A | P28223 | 5/20 | 0.54 |
| ▸ | HTR6 | P50406 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.52 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5166426 | 0.99 | OPRL1 (0.77) | OPRL1OPRM1HTR2AHTR6ALDH1A1 | |
| SCHEMBL5164068 | 0.89 | OPRL1 (0.71) | OPRL1OPRM1MAPT | |
| SCHEMBL5166857 | 0.87 | OPRL1 (0.80) | OPRL1OPRM1HTR2AALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL5164725 | 0.87 | OPRL1 (0.81) | OPRL1OPRM1HTR2AALDH1A1MAPT | |
| SCHEMBL5163332 | 0.87 | OPRL1 (1.00) | OPRL1OPRM1MTNR1AMTNR1B | |
| SCHEMBL5164757 | 0.87 | OPRL1 (0.79) | OPRL1OPRM1HTR2AALDH1A1MAPT | |
| SCHEMBL5163716 | 0.86 | OPRL1 (1.00) | OPRL1OPRM1HTR2AALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL5167045 | 0.86 | OPRL1 (0.79) | OPRL1OPRM1HTR2AALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL5164886 | 0.86 | OPRL1 (1.00) | OPRL1OPRM1HTR2AMTNR1AMTNR1B | |
| Hydrochloric Acid SCHEMBL5165408 | 0.85 | OPRL1 (1.00) | OPRL1OPRM1HTR2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392641-B1 | SUBSTITUTED CYCLOHEXANE-1,4-DIAMINE DERIVATIVES | GRUENENTHAL GMBH (DE) | 2007-04-11 | — | — | EP | claimed |