Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.60 |
| ▸ | CA2 | P00918 | 3/20 | 0.60 |
| ▸ | CA12 | O43570 | 2/20 | 0.60 |
| ▸ | CA9 | Q16790 | 1/20 | 0.60 |
| ▸ | HTR6 | P50406 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 5/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.49 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | AHR | P35869 | 3/20 | 0.47 |
| ▸ | CMA1 | P23946 | 1/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CDK8 | P49336 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31497301 | 1.00 | CA1 (0.60) | CA1CA2CA12CA9HTR6 | |
| Hydrochloric Acid SCHEMBL5241443 | 0.98 | CA1 (0.58) | CA1CA2CA12CA9HTR6 | |
| SCHEMBL516725 | 0.85 | CA1 (0.75) | CA1CA2CA12CA9LMNA | |
| Hydrochloric Acid SCHEMBL19211662 | 0.83 | CA1 (0.73) | CA1CA2CA12CA9LMNA | |
| SCHEMBL7137662 | 0.82 | MEN1 (0.66) | CA1CA2HTR6ESR1CYP19A1 | |
| SCHEMBL1035779 | 0.81 | ESR1 (0.53) | CA1CA2CA12CA9HTR6 | |
| SCHEMBL1144770 | 0.81 | ESR1 (0.53) | CA1CA2CA12CA9HTR6 | |
| SCHEMBL1120379 | 0.81 | TYR (0.52) | CA1CA2CA12CA9HTR6 | |
| SCHEMBL30260844 | 0.81 | ESR1 (0.53) | CA1CA2CA12CA9HTR6 | |
| Hydrochloric Acid SCHEMBL28101627 | 0.79 | TYR (0.50) | CA1CA2CA12CA9HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 102 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105272904-B | N- phenylamide compound and its application | 中国科学院广州生物医药与健康研究院 | 2019-04-09 | — | — | CN | claimed |
| CN-104530014-B | Sulfamide compound of the dihydrobenzo of 2 oxo 1,2 [cd] indoles 6 and combinations thereof and application | 中国科学院广州生物医药与健康研究院 | 2018-03-20 | — | — | CN | claimed |
| EP-3233845-A1 | PARG INHIBITORY COMPOUNDS | Cancer Research Technology Limited (GB) | 2017-10-25 | — | — | EP | claimed |
| CN-107295799-A | Parg inhibiting compounds | 癌症研究科技有限公司 | 2017-10-24 | — | — | CN | claimed |
| CN-105985282-A | 2-oxo-1, 2-dihydrobenzo [ cd ] indole compound and application thereof | 中国科学院广州生物医药与健康研究院 | 2016-10-05 | — | — | CN | claimed |
| WO-2016097749-A1 | PARG INHIBITORY COMPOUNDS | CANCER RESEARCH TECHNOLOGY LIMITED (GB) | 2016-06-23 | — | — | WO | claimed |
| CN-105272904-A | N-phenylamide compound and application thereof | GUANGZHOU INST BIOMED & HEALTH | 2016-01-27 | — | — | CN | claimed |
| CN-104530014-A | 2-oxo-1,2-dihydrobenzo[cd] indole-6-sulfamide compound and composition and application thereof | GUANGZHOU INST BIOMED & HEALTH | 2015-04-22 | — | — | CN | claimed |
| EP-2523559-A1 | COMPOUNDS AND METHODS | GlaxoSmithKline LLC (US) | 2012-11-21 | — | — | EP | claimed |
| CN-101044114-B | Nitrobenzindoles and their use in cancer therapy | AUCKLAND UNISERVICES LTD. (NZ) | 2012-02-15 | — | — | CN | claimed |
| WO-2011088027-A1 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2011-07-21 | — | — | WO | claimed |
| EP-1869010-A1 | 3-SULFONYLAMINO-PYRROLIDINE-2-ONE DERIVATIVES AS FACTOR XA INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-12-26 | — | — | EP | claimed |
| CN-101044114-A | Nitrobenzindoles and their use in cancer therapy | AUCKLAND UNISERVICES LTD (NZ) | 2007-09-26 | — | — | CN | claimed |
| EP-1786770-A1 | N-(1-(2,3-DIHYDRO-1H-INDEN-5YL) -2-OXO-3-PYRROLIDINYL) -SULFONAMIDE DERIVATIVES FOR USE AS FACTOR XA INHIBITORS | GLAXO GROUP LIMITED (GB) | 2007-05-23 | — | — | EP | claimed |
| WO-2006108709-A1 | 3-SULFONYLAMINO-PYRROLIDINE-2-ONE DERIVATIVES AS FACTOR XA INHIBITORS | GLAXO GROUP LIMITED (GB) | 2006-10-19 | — | — | WO | claimed |
| WO-2006027186-A1 | N-(1-(2,3-DIHYDRO-1H-INDEN-5YL) -2-OXO-3-PYRROLIDINYL) -SULFONAMIDE DERIVATIVES FOR USE AS FACTOR XA INHIBITORS | GLAXO GROUP LIMITED (GB) | 2006-03-16 | — | — | WO | claimed |
| CN-1162596-A | Antiarrhythmic Agents | AMERICAN CYANAMID CO (US) | 1997-10-22 | — | — | CN | claimed |
| EP-0230035-B1 | Omega-[(hetero)alkyl]benz[cd]indol-2-amines | AMERICAN CYANAMID CO (US) | 1994-10-12 | — | — | EP | claimed |
| CN-119798210-B | Preparation method of high-purity glycolide | 山东金特安全科技有限公司 | 2025-05-20 | — | — | CN | disclosed |
| US-4615966-A | Color transfer photographic processes and products with indole phthalein filter dyes | POLAROID CORPORATION (US) | 1986-10-07 | — | — | US | disclosed |