SCHEMBL5166142

SCHEMBL5166142

CCNCC(C#N)C#N

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5165807 0.79 ANPEP (0.38)
SCHEMBL11688889 0.76
SCHEMBL11801733 0.74
SCHEMBL262159 0.72
SCHEMBL5168690 0.71
SCHEMBL11689852 0.70 KDM4E (0.31)
SCHEMBL11797854 0.70
SCHEMBL11750994 0.69 CA12 (0.43)
SCHEMBL28983504 0.69
Diethylamine SCHEMBL1985592 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0913388-A1 Hydrogenation of nitriles to produce amines AIR PRODUCTS AND CHEMICALS, INC. (US) 1999-05-06 EP claimed
US-5869653-A USING SPONGE OR RANEY COBALT CATALYST; AMMONIA-FREE REACTION AIR PRODUCTS AND CHEMICALS, INC. (US) 1999-02-09 US claimed
CN-108530636-B Single functionalized branched polyethylene glycol 厦门赛诺邦格生物科技股份有限公司 2021-05-28 CN disclosed
CN-108530637-B Preparation method of single-functionalized branched polyethylene glycol 厦门赛诺邦格生物科技股份有限公司 2021-03-30 CN disclosed
CN-108530637-A A kind of preparation method of simple function branched polyethylene glycol 厦门赛诺邦格生物科技股份有限公司 2018-09-14 CN disclosed
CN-108530636-A A kind of single functionalization branched polyethylene glycol 厦门赛诺邦格生物科技股份有限公司 2018-09-14 CN disclosed
EP-1221436-B1 Process for the preparation of secondary amines from nitriles BASF AG (DE) 2007-04-18 EP disclosed
EP-1221437-B1 Process for the preparation of primary and secondary amines from nitriles BASF AG (DE) 2005-07-06 EP disclosed
US-6790995-B2 BY REDUCTION WITH HYDROGEN AT GIVEN TEMPERATURE AND PRESSURIZATION USING A PALLADIUM-CONTAINING CATALYST ON A SUPPORT; INCREASED OPERATING LIFE OR LONG-TERM STABILITY OF THE CATALYST BASF AKTIENGESELLSCHAFT (DE) 2004-09-14 US disclosed
EP-0869113-B1 Process for the preparation of tertiary amines fromnitriles and secondary amines BASF AG (DE) 2003-06-04 EP disclosed
US-6525223-B2 Reacting nitriles with hydrogen at from at 20-250 degrees C. and pressures of 60-350 bar in the presence of a catalyst of supported rhodium; returning the primary amines separated from the mixtures to the reaction; symmetry BASF AKTIENGESELLSCHAFT (DE) 2003-02-25 US disclosed
US-20020128513-A1 Preparation of secondary amines from nitriles BASF AKTIENGESELLSCHAFT (DE) 2002-09-12 US disclosed
EP-1221436-A2 Process for the preparation of secondary amines from nitriles BASF AKTIENGESELLSCHAFT (DE) 2002-07-10 EP disclosed
EP-1221437-A1 Process for the preparation of primary and secondary amines from nitriles BASF AKTIENGESELLSCHAFT (DE) 2002-07-10 EP disclosed
WO-1999032429-A2 METHOD FOR PRODUCING SECONDARY AMINES FROM NITRILES AND PRIMARY AMINES BASF AKTIENGESELLSCHAFT (DE) 1999-07-01 WO disclosed
EP-0673918-B1 Process for the preparation of peralkylated amines BASF AG (DE) 1999-06-02 EP disclosed
US-5894074-A Preparation of tertiary amines from nitriles and secondary amines BASF AKTIENGESELLSCHAFT (DE) 1999-04-13 US disclosed
EP-0869113-A2 Process for the preparation of tertiary amines fromnitriles and secondary amines BASF AKTIENGESELLSCHAFT (DE) 1998-10-07 EP disclosed
EP-0673918-A1 Process for the preparation of peralkylated amines BASF AKTIENGESELLSCHAFT (DE) 1995-09-27 EP disclosed