Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.74 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | MMP14 | P50281 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid SCHEMBL11282590 | 0.97 | TSHR (0.71) | TSHRCYP3A4TDP1ATMRECQL | |
| Acrylic Acid Ethyl Ester SCHEMBL11247075 | 0.96 | TSHR (0.69) | TSHRCYP3A4TDP1ATMRECQL | |
| SCHEMBL560438 | 0.96 | TSHR (0.81) | TSHRCYP3A4TDP1ATMRECQL | |
| Acrylic Acid SCHEMBL16151343 | 0.95 | TSHR (0.67) | TSHRCYP3A4TDP1ATMRECQL | |
| Acrylic Acid SCHEMBL560619 | 0.93 | TSHR (0.64) | TSHRCYP3A4TDP1ATMRECQL | |
| SCHEMBL6133965 | 0.91 | TSHR (0.72) | TSHRCYP3A4TDP1ATMRECQL | |
| Acrylic Acid SCHEMBL2282780 | 0.91 | TSHR (0.91) | TSHRCYP3A4TDP1ATMRECQL | |
| SCHEMBL6133318 | 0.90 | TSHR (0.71) | TSHRCYP3A4TDP1ATMRECQL | |
| SCHEMBL8746231 | 0.90 | TSHR (0.62) | TSHRCYP3A4TDP1ATMRECQL | |
| Acrylic Acid Methyl Ester SCHEMBL28779743 | 0.89 | TSHR (0.59) | TSHRCYP3A4TDP1ATMRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2399607-B1 | TRANSDERMAL PREPARATION | HISAMITSU PHARMACEUTICAL CO (JP) | 2017-11-29 | — | — | EP | disclosed |
| US-8702664-B2 | Transdermal preparation | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 2014-04-22 | — | — | US | disclosed |
| US-20120031047-A1 | METHOD FOR STORING TRANSDERMALLY/TRANSMUCOSALLY ABSORBABLE PREPARATION AND PACKAGE OF TRANSDERMALLY/TRANSMUCOSALLY ABSORBABLE PREPARATION | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 2012-02-09 | — | — | US | disclosed |
| US-20120029446-A1 | TRANSDERMAL PREPARATION | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 2012-02-02 | — | — | US | disclosed |