Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBFB | Q13951 | 2/20 | 0.49 |
| ▸ | CACNA1H | O95180 | 12/20 | 0.40 |
| ▸ | CACNA1G | O43497 | 5/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 4/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 3/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.36 |
| ▸ | DHODH | Q02127 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4193029 | 0.93 | CBFB (0.51) | CBFBCACNA1HCACNA1GCACNA1CCACNA1B | |
| SCHEMBL904568 | 0.87 | CBFB (0.56) | CBFBCACNA1HCACNA1GCACNA1CCACNA1B | |
| Hydrochloric Acid SCHEMBL4193032 | 0.86 | CBFB (0.55) | CBFBCACNA1HCACNA1GCACNA1CCACNA1B | |
| SCHEMBL4179849 | 0.85 | TRPV1 (0.53) | CBFBCACNA1HCACNA1GCACNA1CCACNA1B | |
| SCHEMBL4186864 | 0.84 | CBFB (0.53) | CBFBCACNA1HCACNA1GCACNA1CCACNA1B | |
| SCHEMBL4189178 | 0.84 | CBFB (0.50) | CBFBCACNA1HCACNA1GCACNA1CCACNA1B | |
| SCHEMBL4191057 | 0.81 | CBFB (0.65) | CBFBTRPV1 | |
| SCHEMBL16121400 | 0.80 | CBFB (0.52) | CBFBCACNA1HCACNA1GCACNA1CCACNA1B | |
| SCHEMBL904608 | 0.78 | CBFB (0.67) | CBFBTRPV1NPBWR1DHODHEGLN1 | |
| SCHEMBL4184178 | 0.77 | TRPV1 (0.51) | CBFBTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1861387-A1 | NOVEL BENZOIMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2007-12-05 | — | — | EP | disclosed |
| WO-2006080821-A1 | NOVEL BENZOIMIDAZOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITION COMPRISING THE SAME | DAEWOONG PHARMACEUTICAL CO., LTD. (KR) | 2006-08-03 | — | — | WO | disclosed |