Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 20/20 | 0.58 |
| ▸ | CTSD | P07339 | 8/20 | 0.53 |
| ▸ | BACE2 | Q9Y5Z0 | 7/20 | 0.53 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4516455 | 0.91 | BACE1 (0.72) | BACE1CTSDBACE2 | |
| SCHEMBL4514009 | 0.87 | BACE1 (0.71) | BACE1CTSDBACE2 | |
| SCHEMBL5132684 | 0.81 | BACE1 (0.57) | BACE1CTSDBACE2 | |
| SCHEMBL5148525 | 0.80 | BACE1 (0.52) | BACE1CTSDBACE2 | |
| SCHEMBL4527878 | 0.79 | BACE1 (0.78) | BACE1CTSDBACE2 | |
| SCHEMBL4525505 | 0.78 | BACE1 (0.72) | BACE1CTSDBACE2 | |
| SCHEMBL7874779 | 0.78 | BACE1 (0.58) | BACE1CTSDBACE2APP | |
| SCHEMBL4511016 | 0.77 | BACE1 (0.65) | BACE1CTSDBACE2 | |
| SCHEMBL5132234 | 0.77 | BACE1 (0.56) | BACE1CTSDBACE2 | |
| Hydrochloric Acid SCHEMBL4857222 | 0.76 | BACE1 (0.59) | BACE1CTSDBACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008076043-A1 | NOVEL 2-AMINO-5,5-DIARYL-IMIDAZOL-4-ONES | ASTRAZENECA AB (SE) | 2008-06-26 | — | — | WO | claimed |