Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 10/20 | 0.68 |
| ▸ | ADH1B | P00325 | 1/20 | 0.52 |
| ▸ | ADH1C | P00326 | 1/20 | 0.52 |
| ▸ | ADH1A | P07327 | 1/20 | 0.52 |
| ▸ | ADH4 | P08319 | 1/20 | 0.52 |
| ▸ | ADH7 | P40394 | 1/20 | 0.52 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.52 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.51 |
| ▸ | CASP2 | P42575 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL967995 | 0.98 | EPHX1 (0.72) | EPHX1ADH1BADH1CADH1AADH4 | |
| SCHEMBL10867937 | 0.93 | EPHX1 (0.61) | EPHX1ADH1BADH1CADH1AADH7 | |
| SCHEMBL966939 | 0.84 | — | — | |
| SCHEMBL9390 | 0.84 | EPHX1 (0.95) | EPHX1EPHX2CASP2SMN1; SMN2 | |
| SCHEMBL10545742 | 0.82 | EPHX1 (0.47) | EPHX1ADH1BADH1CADH1AADH4 | |
| SCHEMBL25271304 | 0.81 | EPHX1 (1.00) | EPHX1ZDHHC20ZDHHC2EPHX2CASP2 | |
| SCHEMBL25223702 | 0.81 | EPHX1 (1.00) | EPHX1ZDHHC20ZDHHC2EPHX2CASP2 | |
| SCHEMBL25228459 | 0.81 | EPHX1 (1.00) | EPHX1ZDHHC20ZDHHC2EPHX2CASP2 | |
| SCHEMBL25278283 | 0.81 | EPHX1 (1.00) | EPHX1ZDHHC20ZDHHC2EPHX2CASP2 | |
| SCHEMBL25227881 | 0.81 | EPHX1 (1.00) | EPHX1ZDHHC20ZDHHC2EPHX2CASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1768973-B1 | SUBSTITUTED QUINOLONES | AICURIS GMBH & CO KG (DE) | 2007-12-05 | — | — | EP | disclosed |
| EP-1768973-A1 | SUBSTITUTED QUINOLONES | AiCuris GmbH & Co. KG (DE) | 2007-04-04 | — | — | EP | disclosed |
| WO-2006008046-A1 | SUBSTITUTED QUINOLONES | AICURIS GMBH & CO. KG (DE) | 2006-01-26 | — | — | WO | disclosed |