Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL605397 | 1.00 | PDE4A (0.50) | PDE4ALMNAL3MBTL1TDP1OR51E2 | |
| SCHEMBL30184358 | 1.00 | PDE4A (0.50) | PDE4ALMNAL3MBTL1TDP1OR51E2 | |
| SCHEMBL23728425 | 1.00 | PDE4A (0.50) | PDE4ALMNAL3MBTL1TDP1OR51E2 | |
| SCHEMBL12349812 | 0.84 | OR51E2 (0.46) | PDE4ALMNAL3MBTL1TDP1OR51E2 | |
| SCHEMBL711439 | 0.84 | OR51E2 (0.46) | PDE4ALMNAL3MBTL1TDP1OR51E2 | |
| SCHEMBL31174574 | 0.84 | OR51E2 (0.46) | PDE4ALMNAL3MBTL1TDP1OR51E2 | |
| SCHEMBL23728418 | 0.84 | OR51E2 (0.46) | PDE4ALMNAL3MBTL1TDP1OR51E2 | |
| SCHEMBL11649679 | 0.84 | OR51E2 (0.46) | PDE4ALMNAL3MBTL1TDP1OR51E2 | |
| SCHEMBL8346473 | 0.84 | OR51E2 (0.46) | PDE4ALMNAL3MBTL1TDP1OR51E2 | |
| SCHEMBL7782071 | 0.84 | OR51E2 (0.46) | PDE4ALMNAL3MBTL1TDP1OR51E2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070280918-A1 | Multitherapy Against Cancer | SCHWARTZ, LAURENT, MR. (FR) | 2007-12-06 | — | — | US | disclosed |
| EP-1771164-A1 | MULTITHERAPY AGAINST CANCER | Schwartz, Laurent (FR) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006016062-A1 | MULTITHERAPY AGAINST CANCER | SCHWARTZ LAURENT (FR) | 2006-02-16 | — | — | WO | disclosed |