Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL531533 | 0.90 | CETP (0.60) | CETPNR1I2 | |
| SCHEMBL531654 | 0.83 | CETP (0.54) | CETPNR1I2 | |
| SCHEMBL531379 | 0.80 | CETP (0.63) | CETPNR1I2 | |
| SCHEMBL5165509 | 0.80 | CETP (0.54) | CETPNR1I2 | |
| SCHEMBL532086 | 0.79 | CETP (0.60) | CETPNR1I2 | |
| SCHEMBL5179065 | 0.79 | CETP (0.60) | CETPNR1I2 | |
| SCHEMBL5167855 | 0.78 | CETP (0.59) | CETPNR1I2 | |
| SCHEMBL9885317 | 0.78 | CETP (0.64) | CETPNR1I2 | |
| SCHEMBL3301815 | 0.78 | CETP (0.66) | CETPNR1I2 | |
| SCHEMBL531402 | 0.78 | CETP (0.54) | CETPNR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765793-A1 | CETP INHIBITORS | Merck and Co., Inc. (US) | 2007-03-28 | — | — | EP | disclosed |
| WO-2006014357-A1 | CETP INHIBITORS | MERCK & CO., INC. (US) | 2006-02-09 | — | — | WO | disclosed |
| WO-2006014413-A1 | CETP INHIBITORS | MERCK & CO., INC. (US) | 2006-02-09 | — | — | WO | disclosed |