SCHEMBL5167754

SCHEMBL5167754

C/C(=C/C(=O)O)C(=O)O[Si](C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.33
KMT2A Q03164 1/20 0.33
POLB P06746 2/20 0.32
MAPT P10636 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
ALDH1A1 P00352 2/20 0.32
KDM4E B2RXH2 1/20 0.32
PKM P14618 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5164501 1.00 HTT (0.33) HTTKMT2APOLBMAPTTDP1
SCHEMBL28605109 0.82 HTT (0.33) HTTALDH1A1
SCHEMBL31741817 0.82
SCHEMBL5167752 0.82
SCHEMBL9709244 0.79 HTT (0.33) HTTALDH1A1KDM4E
SCHEMBL27601496 0.79 MEN1 (0.35) KMT2A
SCHEMBL27601770 0.79 MEN1 (0.35) KMT2A
SCHEMBL9156227 0.78 MAPT (0.31) MAPT
SCHEMBL10699396 0.78 MAPT (0.31) MAPT
SCHEMBL27620010 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1476509-B1 SELF-POLISHING ANTIFOULING PAINT JOTUN AS (NO) 2007-04-11 EP disclosed
EP-1476509-A2 SELF-POLISHING ANTIFOULING PAINT Jotun AS (NO) 2004-11-17 EP disclosed
WO-2003070832-A2 SELF-POLISHING ANTIFOULING PAINT JOTUN AS (NO) 2003-08-28 WO disclosed