Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21152328 | 0.86 | NOTUM (0.72) | NOTUMLMNATP53SMN1; SMN2KMT2A | |
| SCHEMBL3891046 | 0.78 | NOTUM (0.60) | NOTUMLMNATP53SMN1; SMN2KMT2A | |
| SCHEMBL4581917 | 0.78 | NOTUM (0.60) | NOTUMLMNATP53SMN1; SMN2KMT2A | |
| SCHEMBL29556202 | 0.78 | MAPT (0.61) | NOTUMLMNATP53SMN1; SMN2KMT2A | |
| SCHEMBL10627585 | 0.78 | NOTUM (0.60) | NOTUMLMNATP53SMN1; SMN2KMT2A | |
| SCHEMBL3819681 | 0.78 | NOTUM (0.61) | NOTUMLMNATP53SMN1; SMN2KMT2A | |
| SCHEMBL1960697 | 0.78 | MAPT (0.61) | NOTUMLMNATP53SMN1; SMN2KMT2A | |
| SCHEMBL21150838 | 0.78 | NOTUM (0.63) | NOTUMLMNATP53SMN1; SMN2KMT2A | |
| SCHEMBL3369534 | 0.78 | NOTUM (0.60) | NOTUMLMNATP53SMN1; SMN2KMT2A | |
| SCHEMBL917714 | 0.78 | NOTUM (0.67) | NOTUMLMNATP53SMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773125-A1 | 5-IODOTETRAZOLES | Lanxess Deutschland GmbH (DE) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006012996-A1 | 5-IODOTETRAZOLES | LANXESS DEUTSCHLAND GMBH (DE) | 2006-02-09 | — | — | WO | disclosed |