⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7956129 | 1.00 | — | — | |
| SCHEMBL3366057 | 1.00 | — | — | |
| SCHEMBL3366060 | 1.00 | — | — | |
| SCHEMBL7207357 | 0.97 | — | — | |
| SCHEMBL1111568 | 0.89 | — | — | |
| SCHEMBL1111572 | 0.89 | — | — | |
| SCHEMBL1632880 | 0.85 | — | — | |
| SCHEMBL1633317 | 0.85 | — | — | |
| SCHEMBL1633318 | 0.85 | — | — | |
| Hydrochloric Acid SCHEMBL1632913 | 0.84 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198315-B2 | Therapeutic substituted cyclic lactams | ALLERGAN, INC. (US) | 2012-06-12 | — | — | US | disclosed |
| US-20100160407-A1 | THERAPEUTIC SUBSTITUTED CYCLIC LACTAMS | ALLERGAN, INC. (US) | 2010-06-24 | — | — | US | disclosed |
| EP-1385526-B1 | 3, 7 THIA PROSTANOIC ACID DERIVATIVES AS AGENTS FOR LOWERING INTRAOCULAR PRESSURE | ALLERGAN INC (US) | 2007-04-18 | — | — | EP | disclosed |
| EP-1385526-A2 | 3, 7 OR 3 AND 7 THIA OR OXA PROSTANOIC ACID DERIVATIVES AS AGENTS FOR LOWERING INTRAOCULAR PRESSURE | Allergan, Inc. (US) | 2004-02-04 | — | — | EP | disclosed |
| US-20030186939-A1 | Omega-cycloalkyl-prostaglandin E2 derivatives | TANI KOUSUKE (JP) | 2003-10-02 | — | — | US | disclosed |
| US-6613932-B1 | Prostaglandin derivatives | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2003-09-02 | — | — | US | disclosed |
| US-6576785-B1 | ω-cycloalkyl-prostaglandin E2 derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 2003-06-10 | — | — | US | disclosed |
| WO-2002089813-A2 | 3, 7 OR 3 AND 7 THIA OR OXA PROSTANOIC ACID DERIVATIVES AS AGENTS FOR LOWERING INTRAOCULAR PRESSURE | ALLERGAN, INC. (US) | 2002-11-14 | — | — | WO | disclosed |
| EP-1219601-A1 | PROSTAGLANDIN DERIVATIVES | TAISHO PHARMACEUTICAL CO., LTD (JP) | 2002-07-03 | — | — | EP | disclosed |
| US-6410591-B1 | VISION DEFECTS | ALLERGAN SALES, INC. | 2002-06-25 | — | — | US | disclosed |
| EP-0860430-B1 | Omega-cycloalkyl-prostaglandin E2 derivatives | ONO PHARMACEUTICAL CO (JP) | 2002-06-12 | — | — | EP | disclosed |
| US-6262293-B1 | CLATHRATE COMPOUNDS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-07-17 | — | — | US | disclosed |
| US-6110969-A | Cycloalkyl-prostaglandin E2 derivatives | ONO PHARMACEUTICAL CO. LTD. (JP) | 2000-08-29 | — | — | US | disclosed |
| EP-0860430-A2 | Omega-cycloalkyl-prostaglandin E2 derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1998-08-26 | — | — | EP | disclosed |