Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 7/20 | 0.67 |
| ▸ | CA1 | P00915 | 1/20 | 0.65 |
| ▸ | CES2 | O00748 | 4/20 | 0.61 |
| ▸ | CES1 | P23141 | 4/20 | 0.61 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Dodecanoate SCHEMBL31443247 | 1.00 | FABP3 (0.67) | FABP3CA1CES2CES1NFKB1 | |
| Decanoic Acid SCHEMBL2637563 | 1.00 | FABP3 (0.67) | FABP3CA1CES2CES1NFKB1 | |
| Heptanoate SCHEMBL18207959 | 1.00 | FABP3 (0.67) | FABP3CA1CES2CES1NFKB1 | |
| Behenic Acid SCHEMBL28995866 | 1.00 | FABP3 (0.67) | FABP3CA1CES2CES1NFKB1 | |
| Dodecanoate SCHEMBL455947 | 1.00 | FABP3 (0.67) | FABP3CA1CES2CES1NFKB1 | |
| Octanoic Acid SCHEMBL3417082 | 1.00 | FABP3 (0.67) | FABP3CA1CES2CES1NFKB1 | |
| Hexanoate SCHEMBL18207962 | 0.98 | CA1 (0.68) | FABP3CA1CES2CES1NFKB1 | |
| Palmitic Acid SCHEMBL1628227 | 0.93 | FABP3 (0.75) | FABP3CA1CES2CES1NFKB1 | |
| Octanoic Acid SCHEMBL1316022 | 0.93 | FABP3 (0.75) | FABP3CA1CES2CES1NFKB1 | |
| Myristic Acid SCHEMBL3765071 | 0.93 | FABP3 (0.75) | FABP3CA1CES2CES1NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0761733-B1 | Rubber compositions and pneumatic tires using the same | BRIDGESTONE CORP (JP) | 2007-05-09 | — | — | EP | claimed |
| EP-0859017-B1 | Aqueous dispersions of polymerizable reactants, catalyst preparations therefor, their preparation and use | ATOFINA CHEM INC (US) | 2002-05-15 | — | — | EP | claimed |
| CN-114230602-A | Silane modified castor oil, room temperature curing sealant and preparation method thereof | 广州市白云化工实业有限公司 | 2022-03-25 | — | — | CN | disclosed |
| EP-0761733-B1 | Rubber compositions and pneumatic tires using the same | BRIDGESTONE CORP (JP) | 2007-05-09 | — | — | EP | disclosed |
| EP-1717268-A1 | Process for the preparation of flowable, curable polyorganosiloxane masses containing reinforcing filler | Wacker Chemie AG (DE) | 2006-11-02 | — | — | EP | disclosed |
| US-5726237-A | COMPOSITION OF A RUBBER AND CARBON BLACK HAVING LOW ROLLING RESISTANCE AND WET SKID RESISTANCE | BRIDGESTONE CORPORATION (JP) | 1998-03-10 | — | — | US | disclosed |
| EP-0761733-A2 | Rubber compositions and pneumatic tires using the same | Bridgestone Corporation (JP) | 1997-03-12 | — | — | EP | disclosed |
| US-4099007-A | N,N-SUBSTITUTED 2,4,5-TRIKETOIMIDAZOLIDINES AND A PROCESS FOR THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1978-07-04 | — | — | US | disclosed |
| US-4096130-A | N,N'substituted 2,4,5-triketoimidazolidines, corresponding resinous polymers and a process for their preparation | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-06-20 | — | — | US | disclosed |
| US-4074007-A | Coating composition | HOECHST AKTIENGESELLSCHAFT (DT) | 1978-02-14 | — | — | US | disclosed |
| US-4018743-A | Process for preparing triketoimidazolidines | HOECHST AKTIENGESELLSCHAFT (DT) | 1977-04-19 | — | — | US | disclosed |
| US-3969290-A | POLYMERS FROM OXAMIDIC ESTERS, POLYISOCYANATES, AND POLYBASIC CARBOXYLIC ACIDS | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-07-13 | — | — | US | disclosed |