Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1491254 | 0.90 | APP (0.52) | APPLMNASLC6A6CYP2C19BLM | |
| SCHEMBL28704557 | 0.88 | APP (0.50) | APPLMNASLC6A6CYP2C19BLM | |
| SCHEMBL16234813 | 0.82 | TP53 (0.61) | APPLMNASLC6A6CYP2C19BLM | |
| SCHEMBL1977489 | 0.79 | — | — | |
| SCHEMBL16234835 | 0.79 | TP53 (0.63) | APPLMNASLC6A6CYP2C19BLM | |
| SCHEMBL28492814 | 0.79 | APP (0.46) | APPLMNASLC6A6CYP2C19BLM | |
| SCHEMBL1270542 | 0.79 | APP (0.61) | APPLMNASLC6A6CYP2C19BLM | |
| SCHEMBL1270406 | 0.79 | APP (0.61) | APPLMNASLC6A6CYP2C19BLM | |
| SCHEMBL922126 | 0.79 | APP (0.61) | APPLMNASLC6A6CYP2C19BLM | |
| SCHEMBL563945 | 0.79 | APP (0.61) | APPLMNASLC6A6CYP2C19BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773916-B1 | PROCESS FOR PREPARATION OF FUNCTIONALIZED POLYIMIDES | SABIC INNOVATIVE PLASTICS IP (NL) | 2014-02-12 | — | — | EP | disclosed |
| EP-1773916-A1 | PROCESS FOR PREPARATION OF FUNCTIONALIZED POLYIMIDES | The General Electric Company (US) | 2007-04-18 | — | — | EP | disclosed |
| US-7148314-B2 | Process for preparation of functionalized polyimides | GENERAL ELECTRIC COMPANY (US) | 2006-12-12 | — | — | US | disclosed |
| WO-2006014448-A1 | PROCESS FOR PREPARATION OF FUNCTIONALIZED POLYIMIDES | GENERAL ELECTRIC COMPANY (US) | 2006-02-09 | — | — | WO | disclosed |
| US-20060009613-A1 | Process for preparation of of functionalized polyimides | GENERAL ELECTRIC COMPANY | 2006-01-12 | — | — | US | disclosed |