Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | FPR1 | P21462 | 2/20 | 0.36 |
| ▸ | FPR2 | P25090 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5169394 | 1.00 | SLC6A2 (0.41) | SLC6A2SLC6A4SLC6A3EGFRMMP1 | |
| SCHEMBL13839202 | 0.75 | NPC1 (0.48) | SLC6A2SLC6A4SLC6A3EGFRMMP1 | |
| Hydrochloric Acid SCHEMBL3812810 | 0.74 | NPC1 (0.47) | SLC6A2SLC6A4SLC6A3EGFRMMP1 | |
| SCHEMBL4217468 | 0.68 | PAK1 (0.48) | LMNARAB9A | |
| SCHEMBL4217461 | 0.68 | PAK1 (0.48) | LMNARAB9A | |
| Hydrochloric Acid SCHEMBL4227057 | 0.68 | PIM2 (0.38) | SLC6A2SLC6A4RAB9A | |
| Hydrochloric Acid SCHEMBL4227052 | 0.68 | PIM2 (0.38) | SLC6A2SLC6A4RAB9A | |
| SCHEMBL14141312 | 0.66 | KCNH2 (0.53) | SLC6A2SLC6A4SLC6A3RAB9ADCUN1D1 | |
| SCHEMBL4230931 | 0.65 | CHEK1 (0.43) | RAB9A | |
| SCHEMBL4230936 | 0.65 | CHEK1 (0.43) | RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1776357-A1 | HYDROXYAMIDE COMPOUNDS HAVING ACTIVITY AS INHIBITORS OF HISTONE DEACETYLASE (HDAC) | Astellas Pharma Inc. (JP) | 2007-04-25 | — | — | EP | disclosed |
| WO-2006016680-A1 | HYDROXYAMIDE COMPOUNDS HAVING ACTIVITY AS INHIBITORS OF HISTONE DEACETYLASE (HDAC) | ASTELLAS PHARMA INC. (JP) | 2006-02-16 | — | — | WO | disclosed |