SCHEMBL516998

SCHEMBL516998

CCCCOC(=O)c1ccc(OC)cc1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.72
CYP1A2 P05177 2/20 0.72
TSHR P16473 2/20 0.72
CYP2C19 P33261 2/20 0.72
SMN1; SMN2 Q16637 2/20 0.72
ESR1 P03372 2/20 0.72
CYP2D6 P10635 1/20 0.72
MAPK1 P28482 1/20 0.72
NR1H2 P55055 1/20 0.72
RNASEL Q05823 1/20 0.72
CYP3A4 P08684 1/20 0.70
CYP2C9 P11712 1/20 0.70
PDE4D Q08499 1/20 0.70
KMT2A Q03164 2/20 0.67
POLB P06746 1/20 0.67
STS P08842 7/20 0.65
HPGD P15428 1/20 0.62
RECQL P46063 1/20 0.62
MAPT P10636 3/20 0.61
NPC1 O15118 3/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1987834 0.97 TSHR (0.68) LMNACYP1A2TSHRCYP2C19SMN1; SMN2
SCHEMBL1322920 0.95 MAPT (0.69) LMNACYP1A2TSHRCYP2C19SMN1; SMN2
SCHEMBL22498317 0.95 MAPT (0.69) LMNACYP1A2TSHRCYP2C19SMN1; SMN2
SCHEMBL5709890 0.95 MAPT (0.69) LMNACYP1A2TSHRCYP2C19SMN1; SMN2
SCHEMBL14373970 0.95 MAPT (0.69) LMNACYP1A2TSHRCYP2C19SMN1; SMN2
SCHEMBL5709943 0.95 MAPT (0.69) LMNACYP1A2TSHRCYP2C19SMN1; SMN2
SCHEMBL10051629 0.95 MAPT (0.69) LMNACYP1A2TSHRCYP2C19SMN1; SMN2
SCHEMBL10337496 0.95 MAPT (0.69) LMNACYP1A2TSHRCYP2C19SMN1; SMN2
SCHEMBL7526389 0.95 MAPT (0.69) LMNACYP1A2TSHRCYP2C19SMN1; SMN2
SCHEMBL28082715 0.95 MAPT (0.69) LMNACYP1A2TSHRCYP2C19SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 93 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3946240-B1 INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL HENKEL AG & CO KGAA (DE) 2025-10-15 EP claimed
US-20220211602-A1 INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL HENKEL AG & CO. KGAA (DE) 2022-07-07 US claimed
EP-3946240-A1 INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL Henkel AG & Co. KGaA (DE) 2022-02-09 EP claimed
CN-113677319-A Increasing the stability of agents for treating keratin materials 汉高股份有限及两合公司 2021-11-19 CN claimed
CN-109096420-B Catalyst for olefin polymerization and olefin polymerization method 中国石油化工股份有限公司 2021-05-11 CN claimed
WO-2020200545-A1 INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL HENKEL AG & CO. KGAA (DE) 2020-10-08 WO claimed
CN-109096420-A A kind of catalyst and olefine polymerizing process for olefinic polymerization 中国石油化工股份有限公司 2018-12-28 CN claimed
CN-109096419-A A kind of catalyst and olefine polymerizing process for olefinic polymerization 中国石油化工股份有限公司 2018-12-28 CN claimed
CN-109096418-A A kind of catalyst and olefine polymerizing process for olefinic polymerization 中国石油化工股份有限公司 2018-12-28 CN claimed
CN-109096425-A A kind of catalyst and olefine polymerizing process for olefinic polymerization 中国石油化工股份有限公司 2018-12-28 CN claimed
EP-2516479-B1 NEW INTERNAL AND EXTERNAL DONOR COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS BASF CORP (US) 2016-04-20 EP claimed
CN-102834420-B Internal and external donor compounds for olefin polymerization catalysts ii BASF CORP. (US) 2014-10-22 CN claimed
CN-102762602-B New internal and external donor compounds for olefin polymerization catalysts BASF CORP 2014-08-13 CN claimed
US-8569195-B2 Internal and external donor compounds for olefin polymerization catalysts II BASF CORPORATION (US) 2013-10-29 US claimed
CN-102834420-A Internal and external donor compounds for olefin polymerization catalysts ii BASF CORP 2012-12-19 CN claimed
EP-2516479-A2 NEW INTERNAL AND EXTERNAL DONOR COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS BASF Corporation (US) 2012-10-31 EP claimed
CN-102762602-A New internal and external donor compounds for olefin polymerization catalysts BASF CORP 2012-10-31 CN claimed
US-8211819-B2 Internal and external donor compounds for olefin polymerization catalysts BASF CORPORATION (US) 2012-07-03 US claimed
WO-2011084691-A2 NEW INTERNAL AND EXTERNAL DONOR COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS BASF CORPORATION (US) 2011-07-14 WO claimed
US-20110152481-A1 Internal and external donor compounds for olefin polymerization catalysts BASF CATALYSTS LLC (US) 2011-06-23 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220211602-A1 INCREASING THE STABILITY OF AGENTS FOR TREATING KERATIN MATERIAL KRT18, CCNA1, CCNA2 LMNA 123/4885CYP1A2 2289/4885TSHR 4604/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.