SCHEMBL5170100

SCHEMBL5170100

CO[Si](C)(C)CNC(=O)C1CNCCO1

nearest known ligand 0.45

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SSTR4 P31391 20/20 0.45
SSTR1 P30872 1/20 0.38
SSTR2 P30874 1/20 0.38
SSTR3 P32745 1/20 0.38
SSTR5 P35346 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8860932 0.80 SSTR4 (0.52) SSTR4SSTR1SSTR2SSTR3SSTR5
SCHEMBL18664465 0.80 SSTR4 (0.52) SSTR4SSTR1SSTR2SSTR3SSTR5
SCHEMBL18664463 0.80 SSTR4 (0.52) SSTR4SSTR1SSTR2SSTR3SSTR5
SCHEMBL1993031 0.79 SSTR4 (0.53) SSTR4SSTR1SSTR2SSTR3SSTR5
SCHEMBL5220792 0.76 SSTR4 (0.48) SSTR4
SCHEMBL22873631 0.76 SSTR4 (0.48) SSTR4
SCHEMBL2910492 0.76 SSTR4 (0.48) SSTR4
SCHEMBL487610 0.76 SSTR4 (0.49) SSTR4SSTR1SSTR2SSTR3SSTR5
SCHEMBL6039537 0.76 SSTR4 (0.49) SSTR4SSTR1SSTR2SSTR3SSTR5
SCHEMBL27877569 0.75 SSTR4 (0.46) SSTR4SSTR1SSTR2SSTR3SSTR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1771457-A1 ORGANOSILICON COMPOUNDS WITH A MASKED ISOCYANATE GROUP Wacker Chemie AG (DE) 2007-04-11 EP disclosed
WO-2006012957-A1 ORGANOSILICON COMPOUNDS WITH A MASKED ISOCYANATE GROUP WACKER CHEMIE AG (DE) 2006-02-09 WO disclosed