SCHEMBL517017

SCHEMBL517017

CCOC(=O)CCS.CCOC(=O)CCS.CCOC(=O)CCS.O=c1[nH]c(=O)[nH]c(=O)[nH]1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.47
ABL1 P00519 4/20 0.43
RIN1 Q13671 4/20 0.43
TDP1 Q9NUW8 4/20 0.43
TSHR P16473 3/20 0.43
CYP1A2 P05177 1/20 0.42
LMNA P02545 2/20 0.42
GAA P10253 2/20 0.41
MGAM O43451 1/20 0.41
SI P14410 1/20 0.41
MGAM2 Q2M2H8 1/20 0.41
ALDH1A1 P00352 4/20 0.41
KDM4E B2RXH2 2/20 0.41
HSD17B10 Q99714 2/20 0.41
HPGD P15428 1/20 0.41
ALOX15 P16050 1/20 0.41
PDE3B Q13370 2/20 0.40
PDE3A Q14432 2/20 0.40
P2RY12 Q9H244 2/20 0.40
CYP4F2 P78329 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL279949 0.85
SCHEMBL28759123 0.84 SMN1; SMN2 (0.50) SMN1; SMN2ABL1RIN1TDP1TSHR
Ammonia Solution, Strong SCHEMBL28196031 0.83
SCHEMBL963759 0.83 GAA (0.52) TDP1TSHRCYP1A2LMNAGAA
Alcohol SCHEMBL29250843 0.81 GAA (0.50) TDP1TSHRCYP1A2LMNAGAA
Ammonia Solution, Strong SCHEMBL28229706 0.81 GAA (0.50) TDP1TSHRCYP1A2LMNAGAA
SCHEMBL29090869 0.80 CYP1A2 (0.45) TDP1TSHRCYP1A2LMNAGAA
Acetic Acid SCHEMBL29032310 0.79 CYP1A2 (0.48) SMN1; SMN2TDP1TSHRCYP1A2LMNA
Succinic Acid SCHEMBL5036195 0.78 ACE (0.48) SMN1; SMN2CYP1A2LMNAGAAMGAM
SCHEMBL5830474 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11078391-B2 Urethane adhesive composition THE YOKOHAMA RUBBER CO., LTD. 2021-08-03 US disclosed
EP-3333237-B1 URETHANE-BASED ADHESIVE COMPOSITION YOKOHAMA RUBBER CO LTD (JP) 2020-09-23 EP disclosed
EP-3208321-B1 TWO-PACK URETHANE ADHESIVE COMPOSITION YOKOHAMA RUBBER CO LTD (JP) 2019-08-14 EP disclosed
US-20180223144-A1 Urethane Adhesive Composition SIKA TECHNOLOGY AG (CH) 2018-08-09 US disclosed
EP-3333237-A1 URETHANE-BASED ADHESIVE COMPOSITION The Yokohama Rubber Co., Ltd. (JP) 2018-06-13 EP disclosed
US-20170260434-A1 Two-Component Urethane-Based Adhesive Composition THE YOKOHAMA RUBBER CO., LTD. (JP) 2017-09-14 US disclosed
EP-3208321-A1 TWO-PACK URETHANE ADHESIVE COMPOSITION The Yokohama Rubber Co., Ltd. (JP) 2017-08-23 EP disclosed
US-20120028037-A1 COMPOSITION AND LAMINATE KIMOTO CO., LTD. (JP) 2012-02-02 US disclosed