Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNQ3 | O43525 | 1/20 | 0.51 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.51 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.51 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PNLIP | P16233 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
| ▸ | PARG | Q86W56 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | MET | P08581 | 1/20 | 0.44 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5170635 | 1.00 | KCNQ3 (0.51) | KCNQ3KCNQ2KCNE1KCNQ1MAPT | |
| SCHEMBL3131474 | 0.88 | KDM4E (0.53) | KCNQ3KCNQ2KCNE1KCNQ1MAPT | |
| SCHEMBL3138644 | 0.87 | MAPT (0.46) | KCNQ3KCNQ2KCNE1KCNQ1MAPT | |
| SCHEMBL3142159 | 0.85 | KCNQ3 (0.67) | KCNQ3KCNQ2KCNE1KCNQ1MAPT | |
| SCHEMBL3138647 | 0.82 | KCNQ3 (0.47) | KCNQ3KCNQ2KCNE1KCNQ1MAPT | |
| SCHEMBL3138650 | 0.82 | KCNQ3 (0.47) | KCNQ3KCNQ2KCNE1KCNQ1MAPT | |
| SCHEMBL3137838 | 0.81 | KDM4E (0.53) | KCNQ3KCNQ2KCNE1KCNQ1MAPT | |
| SCHEMBL8915769 | 0.81 | KDM4E (0.53) | KCNQ3KCNQ2KCNE1KCNQ1MAPT | |
| SCHEMBL3146704 | 0.81 | KCNQ3 (0.52) | KCNQ3KCNQ2KCNE1KCNQ1MAPT | |
| SCHEMBL3142227 | 0.81 | KDM4E (0.52) | KCNQ3KCNQ2KCNE1KCNQ1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120238750-A1 | AROMATIC COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. | 2012-09-20 | — | — | US | disclosed |
| EP-1773797-A2 | AROMATIC COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006014012-A2 | AROMATIC COMPOUNDS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2006-02-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120238750-A1 | AROMATIC COMPOUND | CBR1, CBR3, CYP1A1 | KCNQ3 1570/4885KCNQ2 1451/4885KCNE1 453/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.