SCHEMBL517144

SCHEMBL517144

NC(CO)C1CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4065197 1.00
SCHEMBL517143 1.00
Hydrochloric Acid SCHEMBL15968078 0.97
Hydrochloric Acid SCHEMBL12538843 0.97
Hydrochloric Acid SCHEMBL12538845 0.97
SCHEMBL28380372 0.89 DPP4 (0.33)
SCHEMBL8256253 0.88
SCHEMBL8249868 0.88
SCHEMBL7576851 0.88
SCHEMBL12050782 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 197 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108137606-B Short-acting benzodiazepine derivatives, method for the production thereof and use thereof 四川科伦博泰生物医药股份有限公司 2021-01-26 CN claimed
CN-106892924-B Short-acting benzodiazepine derivatives, method for the production thereof and use thereof 四川科伦博泰生物医药股份有限公司 2021-01-08 CN claimed
US-20180312511-A1 SHORT-ACTING BENZODIAZEPINE DERIVATIVES, PREPARATION METHOD THEREFOR, AND USE THEREOF SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) 2018-11-01 US claimed
EP-3363801-A1 SHORT-ACTING BENZODIAZEPINE DERIVATIVE, PREPARATION METHOD THEREFOR, AND USE THEREOF Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) 2018-08-22 EP claimed
CN-106892924-A Short-acting benzodiazepine * * derivatives, Its Preparation Method And Use 四川科伦博泰生物医药股份有限公司 2017-06-27 CN claimed
EP-2771327-B1 NOVEL PYRAZINE DERIVATIVES HOFFMANN LA ROCHE (CH) 2016-11-16 EP claimed
US-9403808-B2 Pyrazine derivatives HOFFMANN-LA ROCHE INC. (US) 2016-08-02 US claimed
EP-2771327-A1 NOVEL PYRAZINE DERIVATIVES F.HOFFMANN-LA ROCHE AG (CH) 2014-09-03 EP claimed
WO-2013060751-A1 NOVEL PYRAZINE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2013-05-02 WO claimed
US-20130109665-A1 NOVEL PYRAZINE DERIVATIVES HOFFMANN-LA ROCHE INC. (US) 2013-05-02 US claimed
US-12624024-B2 EP2 antagonist compounds RESERVOIR NEUROSCIENCE, INC. (US) 2026-05-12 US disclosed
US-12612414-B2 Nitrile SUMO inhibitors and uses thereof CIT THERAPEUTICS, INC. (US) 2026-04-28 US disclosed
EP-4729127-A2 BCL6 INHIBITORS Cancer Research Technology Limited (GB) 2026-04-22 EP disclosed
US-12583866-B2 Pyrido[2,3-b][1,4]oxazines or tetrahydropyrido[2,3-b][1,4]oxazepines as IAP antagonists BEONE MEDICINES I GMBH (CH) 2026-03-24 US disclosed
EP-4334298-B1 UREA DERIVATIVES WHICH CAN BE USED TO TREAT CANCER SCORPION THERAPEUTICS INC (US) 2026-02-18 EP disclosed
US-20070287704-A1 7-amino-6-chloro-2-piperazin-1-yl-4-pyrrolidin-1-yl-pteridine; central nervous system, respiratory, gastrointestinal or inflammatory diseases; joints, skin or eyes diseases; cancer; phosphodiesterase 4 inhibitors BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2007-12-13 US disclosed
US-7271289-B2 Biphenylcarboxylic amide derivatives as p38 kinase inhibitors SMITHKLINE BEECHAM CORPORATION (US) 2007-09-18 US disclosed
US-20060241179-A1 Biphenylcarboxylic amide derivatives as p38 kinase inhibitors SMITHKLINE BEECHAM CORPORATION (US) 2006-10-26 US disclosed
EP-1611086-A1 BIPHENYLCARBOXYLIC AMIDE DERIVATIVES AS P38 KINASE INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 2006-01-04 EP disclosed
WO-2004089876-A1 BIPHENYLCARBOXYLIC AMIDE DERIVATIVES AS P38 KINEASE INHIBITORS SMITHKLINE BEECHAM CORPORATION (US) 2004-10-21 WO disclosed