SCHEMBL517175

SCHEMBL517175

[C]1COC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18886880 0.63
SCHEMBL3918390 0.63
Oxirane SCHEMBL886925 0.51
Oxirane SCHEMBL973217 0.51
Oxirane SCHEMBL1330900 0.51
SCHEMBL107513 0.51
Oxirane SCHEMBL3587 0.51
Oxirane SCHEMBL11492072 0.51
Oxirane SCHEMBL654963 0.51
Dioxane SCHEMBL9836999 0.46

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023227676-A1 HERBICIDAL MALONIC ACID MONOAMIDES AND MALONAMIDE ESTERS BASF SE (DE) 2023-11-30 WO claimed
CN-116751200-A Tricyclic compounds containing substituted pyridones and methods of using the same 爱彼特生物制药公司 2023-09-15 CN claimed
US-11702427-B2 Substituted 2-pyridone tricyclic compounds, analogues thereof, and methods using same ARBUTUS BIOPHARMA CORPORATION (CA) 2023-07-18 US claimed
US-20230136562-A1 SPIROUREA DERIVATIVES IDORSIA PHARMACEUTICALS LTD (CH) 2023-05-04 US claimed
EP-4143165-A1 SPIROUREA DERIVATIVES Idorsia Pharmaceuticals Ltd (CH) 2023-03-08 EP claimed
CN-115461327-A Spiro urea derivatives 爱杜西亚药品有限公司 2022-12-09 CN claimed
CN-108368424-B Polymerizable compounds and their use in liquid crystal displays 默克专利股份有限公司 2022-06-03 CN claimed
WO-2021219594-A1 SPIROUREA DERIVATIVES IDORSIA PHARMACEUTICALS LTD (CH) 2021-11-04 WO claimed
US-11013726-B2 Substituted pyridinone-containing trycyclic compounds, and methods using same ARBUTUS BIOPHARMA CORPORATION (CA) 2021-05-25 US claimed
CN-112592343-A Polycyclic compound and application thereof as antiviral drug 周雨恬 2021-04-02 CN claimed
EP-2569309-A1 HYDROXYALKYL BENZYL PYRAZOLES, AND USE THEREOF FOR THE TREATMENT OF HYPERPROLIFERATIVE AND ANGIOGENIC DISEASES Bayer Intellectual Property GmbH (DE) 2013-03-20 EP claimed
US-20120214766-A1 CANNABINOID RECEPTOR MODULATORS ARENA PHARMACEUTICALS, INC. 2012-08-23 US claimed
EP-2470508-A1 CANNABINOID RECEPTOR MODULATORS Arena Pharmaceuticals, Inc. (US) 2012-07-04 EP claimed
US-20120028950-A1 Substituted heterocyclylbenzylpyrazoles and use thereof BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) 2012-02-02 US claimed
WO-2011141325-A1 HYDROXYALKYL BENZYL PYRAZOLES, AND USE THEREOF FOR THE TREATMENT OF HYPERPROLIFERATIVE AND ANGIOGENIC DISEASES BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2011-11-17 WO claimed
WO-2011141326-A1 SUBSTITUTED HETEROCYCLYL BENZYL PYRAZOLES, AND USE THEREOF BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2011-11-17 WO claimed
WO-2011025541-A1 CANNABINOID RECEPTOR MODULATORS ARENA PHARMACEUTICALS, INC. (US) 2011-03-03 WO claimed
US-20100022559-A1 BISOXIMES AS FUNGICIDES BAYER CROPSCIENCE AG (DE) 2010-01-28 US claimed
EP-2106214-A2 BISOXIMES AS FUNGICIDES AND ARTHROPODICIDES Bayer CropScience Aktiengesellschaft (DE) 2009-10-07 EP claimed
WO-2008074418-A2 BISOXIMES AS FUNGICIDES AND ARTHROPODICIDES BAYER CROPSCIENCE AKTENGESELLSCHAFT (DE) 2008-06-26 WO claimed