SCHEMBL51748

SCHEMBL51748

CC(C)(C)[SiH2]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2708401 0.72
SCHEMBL5935930 0.72
SCHEMBL3426362 0.61
SCHEMBL2151842 0.61 TSHR (0.43)
SCHEMBL1913 0.61
SCHEMBL8358538 0.61 TSHR (0.43)
SCHEMBL4062894 0.55
SCHEMBL17620634 0.55
Water SCHEMBL11756523 0.55
SCHEMBL11632388 0.55

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 874 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023226332-A1 METHOD FOR PREPARING CARONIC ANHYDRIDE 南通雅本化学有限公司 2023-11-30 WO claimed
WO-2023226331-A1 METHOD FOR PREPARING CARONIC ACID AND DERIVATIVE THEREOF 南通雅本化学有限公司 2023-11-30 WO claimed
US-20230312630-A1 PHOSPHORAMIDITE SYNTHESIS ON-DEMAND AARHUS UNIVERSITET (DK) 2023-10-05 US claimed
US-20230192751-A1 METHOD FOR THE PREPARATION OF OLIGONUCLEOTIDES THE ROYAL INSTITUTION FOR THE ADVANCEMENT OF LEARNING/MCGILL UNIV (CA) 2023-06-22 US claimed
CN-114958025-A Organic small-molecule fluorescent dye and preparation method and application thereof 南京金斯瑞生物科技有限公司 2022-08-30 CN claimed
CN-113396358-A Liquid crystal aligning agent, liquid crystal alignment film using same, and liquid crystal display element 日产化学株式会社 2021-09-14 CN claimed
CN-108084221-B Silicon hetero-fused ring derivative, application thereof and electroluminescent device 武汉尚赛光电科技有限公司 2020-11-06 CN claimed
CN-111689995-A High-solubility triaryl carbon borate and preparation method and application thereof 万华化学集团股份有限公司 2020-09-22 CN claimed
WO-2020158795-A1 LIQUID CRYSTAL ALIGNING AGENT, LIQUID CRYSTAL ALIGNMENT FILM USING SAME, AND LIQUID CRYSTAL DISPLAY ELEMENT 日産化学株式会社 2020-08-06 WO claimed
EP-3191479-B1 \"PROCESS FOR THE PREPARATION OF MACROCYCLIC KETONE ANALOGS OF HALICHONDRIN B OR PHARMACEUTICALLY ACCEPTABLE SALTS AND INTERMEDIATES THEREOF\ CIPLA LTD (IN) 2020-04-08 EP claimed
EP-0337858-B1 Stereo-specific process for the preparation of enantiomers of furo[3,4-c]pyridine, compounds thus obtained and therapeutical compositions based on these compounds SOD CONSEILS RECH APPLIC (FR) 1994-06-08 EP claimed
EP-0272016-B1 2BETA-SUBSTITUTED-METHYLPENICILLANIC ACID DERIVATIVES, AND SALTS AND ESTERS THEREOF TAIHO PHARMACEUTICAL COMPANY LIMITED (JP) 1992-04-08 EP claimed
US-4983629-A 11-haloprostane derivatives, processes for their preparation and their use as medicinal agents SCHERING AKTIENGESELLSCHAFT (DE) 1991-01-08 US claimed
EP-0373423-A1 Substituted 2-pyridones and pyride-2-thiones, process for their preparation and their use in medicine BAYER AG (DE) 1990-06-20 EP claimed
US-4891369-A BETA-LACTAMASE INHIBITORS TAIHO PHARMACEUTICAL COMPANY, LIMITED (JP) 1990-01-02 US claimed
EP-0325130-A2 Substituted pyridines BAYER AG (DE) 1989-07-26 EP claimed
WO-1988008845-A1 DIASTEREOMERIC 5R,6S-6-(1R-HYDROXYETHYL)-2-(CIS-1-OXO-3-THIOLANYLTHIO)-2-PENEM-3-CARBOXYLIC ACIDS PFIZER INC. (US) 1988-11-17 WO claimed
US-4699920-A 9-halo-2-prostaglandin derivatives, processes for the preparation thereof and use thereof as medicinal agents SCHERING AKTIENGESELLSCHAFT (DE) 1987-10-13 US claimed
US-4444788-A Pharmaceutically active 9-chloroprostaglandins SCHERING AKTIENGESELLSCHAFT (DE) 1984-04-24 US claimed
US-4294959-A Selectively protected 4,6-di-O-(aminoglycosyl)-1,3-diaminocyclitols and their production BAYER AKTIENGESELLSCHAFT (DE) 1981-10-13 US claimed