Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.70 |
| ▸ | MEN1 | O00255 | 8/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.70 |
| ▸ | CASP3 | P42574 | 2/20 | 0.70 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.70 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.65 |
| ▸ | LMNA | P02545 | 5/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.61 |
| ▸ | HTT | P42858 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4922490 | 0.95 | MAPT (0.76) | MAPTMEN1KMT2ACASP3SENP7 | |
| SCHEMBL4112129 | 0.93 | MAPT (0.72) | MAPTMEN1KMT2ACASP3SENP7 | |
| SCHEMBL5174209 | 0.87 | MAPT (0.62) | MAPTMEN1KMT2ACASP3SENP7 | |
| SCHEMBL4117283 | 0.84 | MAPT (0.74) | MAPTMEN1KMT2ACASP3SENP7 | |
| SCHEMBL4110966 | 0.83 | MAPT (0.72) | MAPTMEN1KMT2ACASP3SENP7 | |
| SCHEMBL13695918 | 0.82 | MAPT (0.68) | MAPTMEN1KMT2ACASP3SENP7 | |
| SCHEMBL4924813 | 0.82 | TRPV1 (0.69) | MAPTMEN1KMT2ACASP3SENP7 | |
| SCHEMBL4111911 | 0.81 | TRPV1 (0.75) | MAPTMEN1KMT2ACASP3SENP7 | |
| SCHEMBL5174478 | 0.81 | MAPT (0.66) | MAPTMEN1KMT2ACASP3SENP7 | |
| SCHEMBL4916587 | 0.80 | MAPT (0.79) | MAPTMEN1KMT2ACASP3SENP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786422-A2 | ARYL UREA DERIVATIVES FOR TREATING OBESITY | Prosidion Limited (GB) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006018662-A2 | ARYL UREA DERIVATIVES FOR TREATING OBESITY | PROSIDION LIMITED (GB) | 2006-02-23 | — | — | WO | disclosed |