Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 10/20 | 0.47 |
| ▸ | PGR | P06401 | 1/20 | 0.47 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
| ▸ | UBE2M | P61081 | 1/20 | 0.38 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5175018 | 1.00 | AR (0.47) | ARPGRTAS2R14UBE2MDCUN1D1 | |
| SCHEMBL4898593 | 0.89 | AR (0.56) | ARPGR | |
| SCHEMBL4903290 | 0.89 | AR (0.56) | ARPGR | |
| SCHEMBL4898603 | 0.89 | AR (0.56) | ARPGR | |
| SCHEMBL4898542 | 0.86 | AR (0.50) | ARTAS2R14RORC | |
| SCHEMBL4898546 | 0.86 | AR (0.50) | ARTAS2R14RORC | |
| SCHEMBL4905143 | 0.86 | AR (0.50) | ARTAS2R14RORC | |
| SCHEMBL5185000 | 0.83 | AR (0.43) | ARPGRTAS2R14 | |
| SCHEMBL3060299 | 0.79 | AR (0.54) | ARPGR | |
| SCHEMBL4896538 | 0.79 | AR (0.54) | ARPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1747193-A1 | BENZONITRILE DERIVATIVES TO TREAT MUSCULOSKELETAL FRAILTY | Pfizer Products Incorporated (US) | 2007-01-31 | — | — | EP | disclosed |
| WO-2005108351-A1 | BENZONITRILE DERIVATIVES TO TREAT MUSCULOSKELETAL FRAILTY | PFIZER PRODUCTS INC. (US) | 2005-11-17 | — | — | WO | disclosed |