Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 0.74 |
| ▸ | S1PR3 | Q99500 | 8/20 | 0.74 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.60 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL451912 | 0.88 | S1PR1 (0.78) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL16143790 | 0.88 | S1PR1 (0.84) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL451114 | 0.87 | S1PR1 (0.76) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL448231 | 0.87 | S1PR1 (0.76) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL453881 | 0.87 | S1PR1 (0.78) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL1867767 | 0.87 | S1PR1 (0.88) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL4963049 | 0.86 | S1PR1 (0.77) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL4961705 | 0.86 | S1PR1 (0.77) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL4964985 | 0.86 | S1PR1 (0.77) | S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL447657 | 0.86 | S1PR1 (0.74) | S1PR1S1PR3S1PR4S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1760071-A1 | COMPOUND HAVING S1P RECEPTOR BINDING POTENCY AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-03-07 | — | — | EP | disclosed |