Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.63 |
| ▸ | MEN1 | O00255 | 5/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.63 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.63 |
| ▸ | CASP3 | P42574 | 1/20 | 0.63 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 3/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4913481 | 0.90 | MAPT (0.74) | MAPTMEN1KMT2ATRPV1CASP3 | |
| SCHEMBL4118188 | 0.86 | MAPT (0.75) | MAPTMEN1KMT2ATRPV1CASP3 | |
| SCHEMBL4111778 | 0.85 | TRPV1 (0.74) | MAPTMEN1KMT2ATRPV1CASP3 | |
| SCHEMBL4124085 | 0.83 | MAPT (0.81) | MAPTMEN1KMT2ATRPV1CASP3 | |
| SCHEMBL5174478 | 0.80 | MAPT (0.66) | MAPTMEN1KMT2ATRPV1CASP3 | |
| SCHEMBL4920497 | 0.80 | MAPT (0.75) | MAPTMEN1KMT2ATRPV1CASP3 | |
| SCHEMBL4118384 | 0.80 | MAPT (0.76) | MAPTMEN1KMT2ATRPV1CASP3 | |
| SCHEMBL4122958 | 0.79 | MAPT (1.00) | MAPTMEN1KMT2ATRPV1CASP3 | |
| SCHEMBL4912214 | 0.78 | MAPT (0.71) | MAPTMEN1KMT2ATRPV1CASP3 | |
| SCHEMBL4913207 | 0.78 | MAPT (0.77) | MAPTMEN1KMT2ATRPV1CASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1786422-A2 | ARYL UREA DERIVATIVES FOR TREATING OBESITY | Prosidion Limited (GB) | 2007-05-23 | — | — | EP | disclosed |
| WO-2006018662-A2 | ARYL UREA DERIVATIVES FOR TREATING OBESITY | PROSIDION LIMITED (GB) | 2006-02-23 | — | — | WO | disclosed |