Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 10/20 | 0.51 |
| ▸ | TAS2R8 | Q9NYW2 | 2/20 | 0.45 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL4883973 | 0.93 | IGF1R (0.52) | IGF1RTAS2R8 | |
| SCHEMBL2938587 | 0.84 | IGF1R (0.53) | IGF1RTAS2R8 | |
| SCHEMBL2938589 | 0.83 | IGF1R (0.52) | IGF1RTAS2R8 | |
| Trifluoroacetic Acid SCHEMBL4890244 | 0.80 | IGF1R (0.60) | IGF1RNAMPT | |
| SCHEMBL13039129 | 0.79 | IGF1R (0.67) | IGF1RTAS2R8 | |
| SCHEMBL13177520 | 0.79 | IGF1R (0.58) | IGF1RTAS2R8 | |
| SCHEMBL2942354 | 0.77 | IGF1R (0.59) | IGF1RTAS2R8 | |
| SCHEMBL4881731 | 0.76 | IGF1R (0.57) | IGF1RTAS2R8NAMPT | |
| SCHEMBL2935389 | 0.75 | IGF1R (0.56) | IGF1RTAS2R8 | |
| SCHEMBL2932732 | 0.74 | IGF1R (0.72) | IGF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773809-A1 | SUBSTITUTED CYCLIC UREA DERIVATIVES, PREPARATION THEREOF AND PHARMACEUTICAL USE THEREOF AS KINASE INHIBITORS | Aventis Pharma S.A. (FR) | 2007-04-18 | — | — | EP | disclosed |
| WO-2006010643-A1 | SUBSTITUTED CYCLIC UREA DERIVATIVES, PREPARATION THEREOF AND PHARMACEUTICAL USE THEREOF AS KINASE INHIBITORS | AVENTIS PHARMA S.A. (FR) | 2006-02-02 | — | — | WO | disclosed |