Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5162578 | 1.00 | TACR1 (0.42) | TACR1KCNH2 | |
| SCHEMBL5162610 | 1.00 | TACR1 (0.42) | TACR1KCNH2 | |
| SCHEMBL5159079 | 1.00 | TACR1 (0.42) | TACR1KCNH2 | |
| SCHEMBL5163978 | 0.88 | TACR1 (0.44) | TACR1KCNH2 | |
| SCHEMBL5163973 | 0.88 | TACR1 (0.44) | TACR1KCNH2 | |
| SCHEMBL5164229 | 0.86 | TACR1 (0.44) | TACR1KCNH2 | |
| SCHEMBL5164131 | 0.86 | TACR1 (0.44) | TACR1 | |
| SCHEMBL5410366 | 0.85 | TACR1 (0.42) | TACR1KCNH2 | |
| SCHEMBL5159289 | 0.85 | TACR1 (0.42) | TACR1KCNH2 | |
| SCHEMBL5159230 | 0.84 | TACR1 (0.42) | TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756056-A1 | AZA-BICYCLO[3.1.0]HEX-1-YL DERIVATIVES ACTIVE AS NK1 ANTAGONISTS | Pfizer Products Inc. (US) | 2007-02-28 | — | — | EP | claimed |
| WO-2005121085-A1 | AZA-BICYCLO`3.1.0!HEX-1-YL DERIVATIVES ACTIVE AS NK1 ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2005-12-22 | — | — | WO | claimed |