Methacrylic Acid

Methacrylic Acid

SCHEMBL5177458

C=C(C)C(=O)O.C=C(C)C(=O)O.CC(O)C(C)O

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.42
TDP1 Q9NUW8 1/20 0.40
TSHR P16473 1/20 0.37
FFAR3 O14843 1/20 0.35
LCK P06239 1/20 0.35
FYN P06241 1/20 0.35
ALDH1A1 P00352 1/20 0.35
SLC7A5 Q01650 1/20 0.35
TET2 Q6N021 4/20 0.35
TET3 O43151 1/20 0.35
TET1 Q8NFU7 1/20 0.35
HPGD P15428 1/20 0.33
TGFBR1 P36897 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL5179642 1.00 TP53 (0.42) TP53TDP1TSHRFFAR3LCK
Methacrylic Acid SCHEMBL5179645 1.00 TP53 (0.42) TP53TDP1TSHRFFAR3LCK
Methacrylic Acid SCHEMBL18139615 1.00 TP53 (0.42) TP53TDP1TSHRFFAR3LCK
Methacrylic Acid SCHEMBL18140193 1.00 TP53 (0.42) TP53TDP1TSHRFFAR3LCK
Methacrylic Acid SCHEMBL18139800 1.00 TP53 (0.42) TP53TDP1TSHRFFAR3LCK
Methacrylic Acid SCHEMBL18140661 1.00 TP53 (0.42) TP53TDP1TSHRFFAR3LCK
Methacrylic Acid SCHEMBL18139409 1.00 TP53 (0.42) TP53TDP1TSHRFFAR3LCK
Methacrylic Acid SCHEMBL9779318 1.00 TP53 (0.42) TP53TDP1TSHRFFAR3LCK
Methacrylic Acid SCHEMBL18139336 1.00 TP53 (0.42) TP53TDP1TSHRFFAR3LCK
Methacrylic Acid SCHEMBL5177463 1.00 TP53 (0.42) TP53TDP1TSHRFFAR3LCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103232740-A Light curing coating composition for preparing high toughness optical grade hardening film, and corresponding hardening film FSPG HI TECH CO LTD 2013-08-07 CN disclosed
EP-2535375-A1 Compounded composition on VC (co)polymer basis and its production method SOLVAY SA (BE) 2012-12-19 EP disclosed
EP-1606320-B1 CROSSLINKED THREE-DIMENSIONAL POLYMER NETWORK, METHOD FOR PREPARING SAME, SUPPORT MATERIAL COMPRISING SAME AND USES THEREOF CHIROSEP (FR) 2007-06-13 EP disclosed
US-20040265267-A1 Crosslinked three-dimensional polymer network, method for preparing same, support material comprising same and uses thereof CHIROSEP (FR) 2004-12-30 US disclosed
US-6559334-B1 Unsaturated dipeptides form acrylic amide polymers BAYER AKTIENGESELLSCHAFT (DE) 2003-05-06 US disclosed
US-6348429-B1 POLYMERIZATION INITIATOR OF HIGH MOLECULAR WEIGHT DIACYL PEROXIDE AND TERTIARY AMINE; CEMENTS FOR BIOMEDICAL EQUIPMENT, ORTHOPEDICS, DENTISTRY THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2002-02-19 US disclosed
EP-0758268-A4 POLYMER CEMENT COMPOSITIONS AND INITIATORS FOR USE IN THE PREPARATION THEREOF UNIV CALIFORNIA (US) 1999-04-28 EP disclosed
EP-0758268-A1 POLYMER CEMENT COMPOSITIONS AND INITIATORS FOR USE IN THE PREPARATION THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1997-02-19 EP disclosed
US-5510530-A WHEN POLYMERIZED GIVE OPTICALLY ACTIVE POLYMERS WHICH ARE USEFUL AS ADSORBENTS FOR CHROMATOGRAPHIC SEPARATION OF RACEMATES INTO ENANTIOMERS BAYER AKTIENGESELLSCHAFT (DE) 1996-04-23 US disclosed
US-5481026-A ADDITION POLYMERIZABLE TO CHROMATOGRAPHIC SUPPORTS FOR SEPARATION OF RACEMIC MIXTURES BAYER AKTIENGESELLSCHAFT (DE) 1996-01-02 US disclosed
WO-1995030480-A2 INITIATORS OF TERTIARY AMINE/PEROXIDE AND POLYMER THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1995-11-16 WO disclosed
US-5432252-A Acrylamide derivatives; use as polymeric adsorbent in separation of racemic mixtures into their optical antipodes BAYER AKTIENGESELLSCHAFT (DE) 1995-07-11 US disclosed
US-5432251-A Acrylamide derivatives; use as polymeric adsorbent in separation of racemic mixtures into their optical antipodes BAYER AKTIENGESELLSCHAFT (DE) 1995-07-11 US disclosed
US-5357001-A Optically active amino acid sulphoxide and amino acid sulphone derivatives, their preparation, their polymerisation and use as adsorbents for chromatographic resolution of racemates BAYER AKTIENGESELLSCHAFT (DE) 1994-10-18 US disclosed
US-5354884-A Polymer used as adsorbants for the chromatographic resolution of racemates into their enantiomers BAYER AKTIENGESELLSCHAFT (DE) 1994-10-11 US disclosed
US-5348656-A Adsorbants for optical resolution BAYER AKTIENGESELLSCHAFT (DE) 1994-09-20 US disclosed
US-5347042-A Optically active sulphur-containing amino acid derivatives, their preparation, their polymerisation to give optically active polymers and the use thereof BAYER AKTIENGESELLSCHAFT (DE) 1994-09-13 US disclosed
US-5292924-A Optically active N-α-fluoroacryloylamino acid polymers for the resolution of racemates BAYER AKTIENGESELLSCHAFT (DE) 1994-03-08 US disclosed
US-4725629-A Process of making an interpenetrating superabsorbent polyurethane foam KIMBERLY-CLARK CORPORATION (US) 1988-02-16 US disclosed
US-4001368-A CURING DAI NIPPON TORYO CO., LTD. (JA) 1977-01-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040265267-A1 Crosslinked three-dimensional polymer network, method for preparing same, support material comprising same and uses thereof UROD, ALG1, NOTUM TP53 4747/4885TDP1 4095/4885TSHR 4867/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.